4.4 • 1.3K Ratings
🗓️ 18 June 2025
⏱️ 72 minutes
🧾️ Download transcript
Today’s show:
In this episode, @Jason and @alex explore how AI is reshaping the economy—from Pano AI’s $44M raise to fight wildfires with drones, to Amazon CEO Andy Jassy’s memo foreshadowing white-collar job cuts, to Meta’s stealth move poaching Scale AI talent. They dig into the collapse of early-career roles, the slow disappearance of the gig economy safety net, and why founders may want to think twice before building in public.
Timestamps:
(1:52) Travel chaos, laundry issues, and the Airbnb event(3:05) CO2 conference highlights and Zipline drone delivery innovation(5:24) AI’s effect on job disruption and white-collar retraining(09:46) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(11:01) Jassy on AI’s workforce impact and boosting teacher roles(13:23) Media evolution: market resilience and direct communication strategies(20:08) INBOUND - Use code TWIST10 for 10% o your General Admission ticket at https://www.inbound.com/register (Valid thru 7/31)(21:14) OpenAI’s podcast, corporate media shifts, and Twist 500 highlights(30:02) NWRA - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit northwestregisteredagent.com/twist today!(31:20) Insurance, AI, and OpenAI’s enterprise focus(41:11) Meta and Traversal’s AI bets; startup transparency(48:57) TikTok, US-China tension, and data privacy debate(56:43) Actuality.ai’s platform for AI-driven RFPs and enterprise pricing insights(1:11:00) Wrap-up and final thoughts with Rishab Gupta
Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com
Check out the TWIST500: https://www.twist500.com
Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp
Follow Alex:
LinkedIn: https://www.linkedin.com/in/alexwilhelm
Follow Jason:
LinkedIn: https://www.linkedin.com/in/jasoncalacanis
Thank you to our partners:
(09:46) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST
(20:08) INBOUND - Use code TWIST10 for 10% o your General Admission ticket at https://www.inbound.com/register (Valid thru 7/31)
(30:02) NWRA - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit northwestregisteredagent.com/twist today!
Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland
Check out Jason’s suite of newsletters: https://substack.com/@calacanis
Follow TWiST:
Twitter: https://twitter.com/TWiStartups
YouTube: https://www.youtube.com/thisweekin
Instagram: https://www.instagram.com/thisweekinstartups
TikTok: https://www.tiktok.com/@thisweekinstartups
Substack: https://twistartups.substack.com
Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
Click on a timestamp to play from that location
0:00.0 | I want to make one more little point about the labor discussion because Andy Jassy, the CEO of Amazon, |
0:05.0 | dropped a public memo yesterday. And the key quote, which I just pulled up. |
0:10.0 | I was thinking like, Jason, it's almost like you're getting the inside scoop. |
0:14.0 | This is what he said about Amazon and their deployment of generative AI products. He says, |
0:20.0 | as we roll out more Gen. |
0:21.9 | AI and agents, it should change the way our work is done. |
0:25.6 | We will need fewer people doing some of the jobs that are being done today and more people |
0:29.8 | doing other types of jobs. |
0:31.3 | It's hard to know exactly where this nets out over time, but in the next few years, |
0:35.1 | we expect that this will reduce our total corporate |
0:37.6 | workforce as we get efficiency gains from using AI extensively across the company. |
0:43.0 | That to me is so, yes, true. |
0:45.3 | I mean, we talk a lot about productivity improvements, and when you have more productive individual |
0:48.9 | units, you need fewer of those units. |
0:51.1 | So that to me is the non-domer take though, because the doomer take is |
0:54.6 | white color works going to evaporate overnight. That's not going to happen. |
1:00.6 | This weekend startups is brought to you by Squarespace. Turn your idea into a new website. |
1:06.0 | Go to Squarespace.com slash twist for a free trial. When you're ready to launch, |
1:09.7 | use offer code Twist to save 10% off your first purchase of a website or domain. |
1:14.4 | Inbound. Connect with visionary leaders like Dario Amade and Amy Poehler at inbound 2025, September 3rd through 5th in San Francisco, the epicenter of tech innovation, and transform your business strategy for the AI era. |
1:26.8 | Use code Twist 10 for 10% off your general admission ticket at inbound.com slash register, |
1:32.0 | valid through July 31st. |
... |
Please login to see the full transcript.
Disclaimer: The podcast and artwork embedded on this page are from Jason Calacanis, and are the property of its owner and not affiliated with or endorsed by Tapesearch.
Generated transcripts are the property of Jason Calacanis and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.
Copyright © Tapesearch 2025.