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NutritionFacts.org Video Podcast

Friday Favorites: The Side Effects of 3-MCPD in Bragg’s Liquid Aminos and Refined Cooking Oils

NutritionFacts.org Video Podcast

Michael Greger, M.D. FACLM

Nutrition, Alternative Health, Health & Fitness

4.8951 Ratings

🗓️ 4 July 2025

⏱️ 8 minutes

🧾️ Download transcript

Summary

Chlorohydrin contaminates hydrolyzed vegetable protein products and refined oils.

Transcript

Click on a timestamp to play from that location

0:00.0

You may see the title to this video and be thinking,

0:03.0

wait, what is 3MCPD?

0:06.0

It's a chlorohydrin, a compound found in items like Bragg's liquid aminos

0:10.0

and soy sauce.

0:11.0

Is it safe?

0:12.0

Watch to find out.

0:18.0

In 1978, chlorhydrins were found in protein hydrolyssates.

0:27.4

What does that mean?

0:29.7

Proteins can be broken down into amino acids using a chemical process called hydrolysis,

0:34.6

and free amino acids like glutamate can have taste-enhancing qualities.

0:38.9

That's how they make cheap soy sauce and seasonings like Bragg's liquid aminos.

0:43.6

This process requires high heat, high pressure, and hydrochloric acid to break apart the protein.

0:48.9

The problem is that when any residual fat is exposed to these conditions, it can form toxic compounds called chlorohydrins.

0:57.0

But when I say toxic, we're talking about toxic to mice and rats.

1:02.0

Chlorhydrants, like 3MCPD, are considered a worldwide problem of food chemistry,

1:08.0

but no clinical studies on humans have been reported so far.

1:12.6

The concern is about detrimental effects on kidneys and fertility.

1:16.6

In fact, there was a time in which it was considered as a potential male contraceptive

1:21.6

because it could so affect sperm production.

1:24.6

However, research funding was withdrawn after unacceptable side effects were observed in primates.

1:31.3

They found flaccid testes in rats, which is what they were going for, but it caused

1:35.6

neurological scars in monkeys.

...

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