Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist, Eric Christensen.

Thank you so much for listening today. As always, go check out Real Life Pharmacology.com.

We've got the free 31 page PDF on the top 200 drugs. It's a great study guide, great refresher.

And also, please support the sponsor MedHead 101.com slash store. We've got tons of resources,

books for board exams, and various items like that. So again, your support there goes directly

to help this podcast. All right. So today I had a request, and I'm going to cover some food supplement interactions.

And one of the first ones I'm going to start out with here is grapefruit juice.

And if you recall, if you're a close follower of the podcast,

I have done a whole episode on grapefruit juice drug interaction.

So not going to spend much time on this, you know, supplement, food, whatever you

want to call it, but recall that it is a SIP-3A-4 inhibitor, and there's a lot of drugs

that are broken down and metabolized by SIP-3A-4.

So just a quick refresher, numerous statins, amiodarone, colchazine,

some of the immunosuppressive agents like Tachrolomus, for example,

calcium channel blockers.

These are all drugs that are broken down significantly by SIP 3A4.

Naturally, they're going to have their concentrations rise,

and we're going to be more likely to have toxicity-type situations with those meds.

So that is grapefruit juice in a nutshell.

Again, if you want more details on that, definitely refer back to a previous podcast episode.

All right.

Next ones, I guess there's three supplements that I've historically heard about in pharmacy school.

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