Fluticasone, Umeclidinium, and Vilanterol Pharmacology
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist
4.9 • 773 Ratings
🗓️ 23 April 2020
⏱️ 12 minutes
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Summary
Fluticasone, Umeclidinium, and Vilanterol is a combination medication used in the setting of COPD. I discuss the pharmacology of this agent further in this episode.
Fluticasone is the inhaled corticosteroid portion of the drug while umeclidinium is a LAMA and vilanterol is a LABA medication.
Drug interactions aren’t incredibly common or strongly clinically significant, but I discuss some of them with Trelegy Ellipta.
Having a once-daily dose can be advantageous to help improve patient adherence. Fluticasone, umeclidinium, and vilanterol comes as a once-daily combination.
I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!
Transcript
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| 0:00.0 | Hey all, welcome back to the real-life pharmacology podcast. I'm your host, Eric Christensen. |
| 0:06.9 | If you want to track us down, check us out at real-life pharmacology.com. Definitely take |
| 0:12.8 | advantage of that free 30-plus page PDF on the top 200 drugs if you're studying for |
| 0:19.5 | pharmacology or just looking to pick up some |
| 0:22.5 | clinical practice pearls. Definitely go snag that PDF for free at real art pharmacology.com |
| 0:29.0 | and we'll also get you updates as far as when we have new podcasts available. |
| 0:36.1 | So the drug I'm going to cover today is a combination product that I am seeing periodically now. |
| 0:44.2 | Fluticazone, umacladinium, and volantorol is the combination. |
| 0:50.6 | So this is an inhaled medication primarily for the use of COPD. |
| 0:58.3 | It's a combination medication, obviously. It's got three different drugs. |
| 1:03.4 | So the Fluticazone is an inhaled corticosteroid. |
| 1:07.8 | Umaclidinium is a long-acting anticholinergic and volantorol is a long-acting |
| 1:13.9 | beta-2 agonist. So one of the big clinical advantages with this medication is its dose once a day |
| 1:26.2 | and we've got three medications within it. |
| 1:31.2 | Now that can be a good and a bad thing. |
| 1:33.7 | Obviously the once daily is a huge advantage for patients. |
| 1:38.4 | It's a very convenient thing to use. |
| 1:41.5 | You can factor it into your daily routine versus a medication |
| 1:45.8 | that, you know, you maybe do two or three times a day. That gets a little bit trickier sometimes |
| 1:51.4 | for some patients to follow that regimen. So more doses you add throughout the day, the more and |
| 1:57.7 | more likely that you're going to see patients skip doses, missed doses, |
| 2:03.2 | forget doses, or whatever the case may be there. |
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