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This Week in Cardiology

Feb 16 2024 This Week in Cardiology

This Week in Cardiology

Medscape Podcasts

Science, Medicine, Health & Fitness

4.9963 Ratings

🗓️ 16 February 2024

⏱️ 24 minutes

🧾️ Download transcript

Summary

An update in trial interpretation, CI, and P-values; percutaneous tricuspid Interventions; and news on HDL and humility in Medicine are the topics John Mandrola, MD, covers in this week's podcast.

This podcast is intended for healthcare professionals only.

To read a partial transcript or to comment, visit:

https://www.medscape.com/twic

I. Evidence of Absence Is not Absence of Evidence

Feb 09, 2024 This Week in Cardiology Podcast

https://www.medscape.com/viewarticle/1000101

  • ARCADIA Trial https://jamanetwork.com/journals/jama/fullarticle/2814933
  • FOURIER Trial https://www.nejm.org/doi/full/10.1056/nejmoa1615664
  • Sample Size Calculator https://clincalc.com/stats/samplesize.aspx

II. Tricuspid Valve Interventions

FDA OKs First Transcatheter Tricuspid Valve Replacement

https://www.medscape.com/viewarticle/fda-oks-first-transcatheter-tricuspid-valve-replacement-2024a10002dq

FDA Panel in Favor of TriClip for Tricuspid Regurgitation

https://www.medscape.com/viewarticle/fda-panel-favor-triclip-tricuspid-regurgitation-2024a100037n

  • Cardiothoracic Surgical Trials Network Study https://www.nejm.org/doi/full/10.1056/NEJMoa2115961
  • TRILUMINATE https://www.nejm.org/doi/full/10.1056/NEJMoa2300525
  • KAUL Tweet on ATTR Cardiomyopathy https://twitter.com/kaulcsmc/status/1753552603534016622?s=20
  • APOLLO B trial https://www.nejm.org/doi/full/10.1056/NEJMoa2300757
  • Al-Lamee Tweet on Sham Controls https://x.com/rallamee/status/1758236588570562736

III. HDL Cholesterol

  • Rationale paper — AEGIS https://doi.org/10.1016/j.ahj.2020.10.052
  • Press Release AEGIS II https://www.prnewswire.com/news-releases/csl-announces-top-line-results-from-the-phase-3-aegis-ii-trial-evaluating-the-efficacy-and-safety-of-csl112-apolipoprotein-a-i-human-302059156.html

You may also like:

The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington

Questions or feedback, please contact news@medscape.net

Transcript

Click on a timestamp to play from that location

0:00.0

You're listening to this week in cardiology from the heart

0:03.4

org medscape cardiology this podcast is intended for health care

0:07.6

professionals only any views expressed are the presenters own and do not

0:11.2

necessarily reflect the views of WebMD or Medscape.

0:15.1

You can now access the latest in medical news on your Amazon Alexa-enabled device.

0:19.7

Join me, Perry Wilson, every weekday morning for Medscape Medical Minute where I highlight the top

0:24.7

medical stories of the day.

0:26.5

To add Medscape Medical Minute to your flash briefing, search for Medscape Medical

0:30.1

Minute on Amazon and click enable or open the Amazon Alexa app go to skills search for

0:35.6

Medscape Medical Minute and click enable then say Alexa what's the news or

0:40.8

Alexa what's my flash briefing I hope you'll join us.

0:44.0

Hi everyone this is John Mandrola from the heart dot org medscape

0:49.0

and this is this week at cardiology for February 16th, 2024.

0:55.0

This week, I'm going to lead with an important update

0:58.0

on a mistake I made in trial interpretation from last week.

1:01.8

It's on conference intervals and p values. I'll talk about

1:05.8

percutaneous tricussive valve interventions and news on HDL and

1:10.6

humility in medicine. First an update on last week.

1:15.0

I want to update my discussion on the Arcadia trial.

1:19.0

Recall that Arcadia tested a pixoban versus aspirin in post-stroke patients who had evidence of

1:26.1

atrial cardiopathy. Atrial cardiopathy could have been diagnosed by an abnormal ECG,

1:32.3

a BMP, or left-a-drill size on echo. My discussion centered on the fact that

...

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