meta_pixel
Tapesearch Logo
Log in
The Highwire with Del Bigtree

FDA APPROVES MERCK’S RSV SHOT DESPITE ALARMING INFANT TRIAL DATA

The Highwire with Del Bigtree

The Highwire with Del Bigtree

Health & Fitness, News, Society & Culture

4.93.3K Ratings

🗓️ 24 June 2025

⏱️ 14 minutes

🧾️ Download transcript

Summary

Del and Jefferey dive into the troubling numbers behind Merck’s new RSV shot for infants, recently greenlit by the FDA. Trial data revealed higher rates of deaths and severe respiratory illness in vaccinated babies, yet the FDA overlooked this concerning trial data.

Become a supporter of this podcast: https://www.spreaker.com/podcast/the-highwire-with-del-bigtree--3620606/support.

Transcript

Click on a timestamp to play from that location

0:00.0

Let's start with the global RSV market. What is RSV? This is respiratory and

0:06.0

antitial virus. It's a common cold for most people, but for the elderly and the infants,

0:11.0

it can lead to hospitalization. So we have a market now developing it with the vaccinations,

0:17.0

and there's vaccinations and there's monoclonal antibodies. So they're both kind of competing for this market in those age groups, the older age groups and then the infants. And you can see here in this kind of overview of the market looking at the 2030 forecasts. It says considering both the modalities antibody and vaccine targeting all three key age groups, the global RSV vaccine and antibody market is expected

0:38.5

to be worth $2.61 billion in 2024 raising to US $13.59 billion by 2030.

0:47.5

Now this has been a market that's been historically plagued with some issues in the clinical

0:52.0

trials in trying to get these vaccines, especially in children.

0:55.5

So when I saw this headline from NBC Chicago, FDA approves Merck's RSV shot for infants

1:02.2

wrapping up competition with Sanofi and AstraZeneca.

1:06.6

This is for newborns and infants.

1:08.3

FDA authorized, authorizes use newborns during the, whether they're entering or during the first

1:16.0

RSV season of their life.

1:17.8

So this is a monoclonal antibody shot.

1:20.8

And let's look at the clinical trials for this.

1:23.5

So all drug companies have to go through clinical trials.gov.

1:27.1

They have to basically state their intentions and any updates on these trials, they have to

1:31.5

post this here.

1:32.8

And this is the final trial.

1:34.4

This was the Merck efficacy and safety of chalcerobamab.

1:38.0

That's their RSV monoclonal antibody shot.

1:41.1

And this is an infant's.

1:42.2

So just to start out here, twice as many people is it's a caveat

...

Please login to see the full transcript.

Disclaimer: The podcast and artwork embedded on this page are from The Highwire with Del Bigtree, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of The Highwire with Del Bigtree and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.

Copyright © Tapesearch 2025.