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As a Woman

Failed IVF Cycles

As a Woman

Natalie Crawford

Medicine, Health & Fitness

4.81.1K Ratings

🗓️ 19 May 2026

⏱️ 27 minutes

🧾️ Download transcript

Summary

In this episode of the As a Woman podcast, host Dr. Natalie Crawford dives deep into the devastating reality of failed IVF cycles to explain why a negative result is not a personal failure, but rather a critical piece of biological data. By shifting the perspective from self-blame to scientific empowerment, Dr. Crawford provides listeners with a comforting yet highly informative roadmap on how to navigate the aftermath of an unsuccessful cycle and prepare for what comes next. What You’ll Learn: The overlooked biological distinctions between the IVF retrieval process and embryo transfer success rates. How specific milestones in egg maturity stages directly influence your overall embryonic potential. The critical timeline phase where poor sperm quality halts development, even with a normal semen analysis. Why maternal age and metabolic health dictate the mathematical odds of genetic normalcy in a blastocyst. The five distinct frozen embryo transfer protocols used to optimize the uterine implantation window. Host Resources: Order The Fertility Formula! ⁠https://www.nataliecrawfordmd.com/book⁠ Newsletter: nataliecrawfordmd.com/newsletter Instagram: @nataliecrawfordmd Youtube Channel: Natalie Crawford MD Interested in becoming a patient?: Fora Fertility Earn FREE CE/CME: Learn at Pinnacle App This episode is brought to you by The Pinnacle Podcast Network.  Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

from sitting in a room with one third of people who just had their first embryo transfer.

0:04.7

And we all didn't get success. You're not alone.

0:07.5

IVF failure is not always random. And I have what we call the WTF.

0:11.1

What went wrong in the cycle? What are your expectations? What does it mean if it's low fur?

0:15.3

Failed IVF cycle is not the end of the story. Isn't it crazy that 30 minutes can make such a big difference there?

0:23.4

Welcome back to the As a Woman podcast. I'm your host, Dr. Natalie Crawford, and today we're

0:27.7

talking about one of the hardest and most emotionally complex experiences in fertility,

0:32.7

and that's failed IVF cycles. When an IVF cycle doesn't work, it can really be devastating.

0:38.5

Many women blame themselves or their bodies or feel like they've run out of options.

0:43.0

But the truth is, IVF failure is not always random, and it's not a personal failure.

0:47.9

It's a biologic outcome, one that we can learn from. In this episode, we're going to talk about

0:52.9

why IVF cycles fail. What's

0:55.0

actually happening at the level of the egg, embryo, and the uterus, and most importantly,

0:59.6

what comes next. Because a failed IVF cycle is not the end of the story. It's just information.

1:05.2

And understanding that information is what allows us to adjust, optimize, and move forward

1:10.0

with clarity. My goal today is to help you

1:12.3

understand the science, take the blame off yourself, and give you a roadmap for what to do next.

1:17.3

All right, friends, I know if you go through IVF, we sometimes just assume it's going to work.

1:22.2

And this mentality can be really devastating if we find ourselves in this circumstance when we have a

1:27.4

negative result

1:28.1

after an IVF cycle. I sit down with patients every day and I have what we call the WTF visit.

1:33.7

What went wrong in the cycle looking at all the different data points so that we can learn about?

...

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