eXoZymes AI-Enhanced Enzymes & The Future Of Sustainable Manufacturing
Finding Genius Podcast
Richard Jacobs
4.4 • 1K Ratings
🗓️ 10 May 2026
⏱️ 17 minutes
🧾️ Download transcript
Summary
Join us in this episode as Tyler Korman, the Chief Scientific Officer and Co-Founder of eXoZymes, explains how their approach to AI-enhanced, cell-free enzyme technology is changing the way chemicals are produced…
Hit play to discover:
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How enzymes are produced in large quantities.
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The ways that enzymes are used in everyday life.
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The role that the microbiome plays in enzyme balance.
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How sequencing data contributes to the creation of new compounds.
Tyler co-founded eXoZymes with Paul Opgenorth, building on research from the Jim Bowie Lab at UCLA. His expertise includes cell-free biomanufacturing, enzyme engineering, and AI-driven design. His work focuses on creating more efficient and sustainable methods for producing complex compounds by operating enzymes outside of living cells.
To learn more about Tyler and his work, connect with him on LinkedIn!
🎧 Listen now on Apple Podcasts: http://apple.co/30PvU9C
🛍️ Recommended Books from this Episode
📖 Enzymes: Biochemistry, Biotechnology, Clinical Chemistry – A comprehensive guide to enzyme science, covering their biological functions, clinical applications, and importance in biotechnology and medicine.
👉 Get it here
📘 Advances in Enzyme Biotechnology – An in-depth look at the latest developments in enzyme research and how biotechnology is transforming industries from healthcare to manufacturing.
👉 Check it out
📙 Enzyme Biotechnology – A practical and scientific exploration of enzyme production, applications, and their growing role in modern biotechnology.
👉 Explore it here
Note: These are affiliate links. If you make a purchase through them, we may earn a small commission at no extra cost to you. It helps support the podcast. Thank you!
Transcript
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| 0:00.0 | Forget frequently asked questions. |
| 0:02.3 | Common sense. |
| 0:03.1 | Common knowledge. |
| 0:04.1 | Or Google. |
| 0:04.7 | How about advice from a real genius? |
| 0:06.9 | 95% of people in any profession are good enough to be qualified in license. |
| 0:11.3 | 5% go above and beyond. |
| 0:13.1 | They become very good at what they do. |
| 0:14.8 | But only 0.1% are real geniuses. |
| 0:18.2 | Richard Jacobs has made it his life's mission to find them for you. |
| 0:22.2 | He hunts down and interviews geniuses in every field. |
| 0:25.1 | Sleep science, cancer, stem cells, ketogenic diets, and more. |
| 0:28.6 | Here come the geniuses. |
| 0:30.3 | This is the Finding Genius podcast with Richard Jacobs. |
| 0:37.3 | Hello, this is Richard Jacobs with the Finding Genius podcast. |
| 0:41.2 | My guest today is Tyler Corman. |
| 0:42.8 | He's a chief scientific officer and co-founder of exosymes. |
| 0:46.8 | It looks like they've innovated an entirely new method of making chemicals by taking enzymes, |
| 0:51.5 | which are molecular workers inside cells, and coaxing and engineering them |
| 0:55.1 | to operate outside a cell. So this is going to allow them to make some really interesting |
| 0:59.1 | structures and chemicals for biological applications. So welcome, Tyler. Thanks for coming. |
| 1:04.2 | Yeah, thanks for having me. Yeah, I'm sure you can express it better. What's the underlying premise of |
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