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Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Ethinyl Estradiol

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist

Education, Health & Fitness, Medicine

5716 Ratings

🗓️ 4 August 2022

⏱️ 13 minutes

🧾️ Download transcript

Summary

On this episode, I cover ethinyl estradiol pharmacology. This is a common component of oral contraceptives. You have to check out this free resource (with free account) from Pyrls.com/rlp which lists all the different combinations and brand names. All it takes is to simply sign up for a free account here.



Ethinyl estradiol dosing can vary. Breakthrough bleeding is a major reason why a patient might prefer a higher dose.



Blood clot risk is a real problem with ethinyl estradiol. There are numerous situations where we should avoid ethinyl estradiol and I cover them in this episode.



Be careful with enzyme inducers like carbamazepine, rifampin, etc. as they can reduce the concentrations of oral contraceptives

Transcript

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0:00.0

Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist, Eric Christensen.

0:05.7

Thank you so much for listening today. As always, go check out Real Life Pharmacology.com.

0:12.2

I've got a free 31-page PDF on the top 200 drugs. It's a great study guide if you're taking any type of board exam or if you're in pharmacology classes going through that in college.

0:26.0

Great resource, great refresher if you're out in practice as well.

0:30.1

So again, totally free simply for subscribing to the podcast by sharing your email there. So with that said, let's get it in the drug of the day

0:40.7

today and that is ethanol estradiol. And I wanted to break these apart a little bit because

0:48.7

ethanol estradiol is part of combined oral contraceptives with a progesterone component.

0:57.5

Obviously, ethanol estradiol is the estrogen type component.

1:03.0

Brand names of those combination oral contraceptives include Sprintech, Jolesa, Apre, Lovora, Cariva, Nottrell, Yaz.

1:16.9

So there's tons and tons of brand name Moro Controceptives,

1:21.7

and each one tends to either have a different dosage of ethanol estradiol and or a different progesterone

1:32.2

component. So that's really what the difference is. So you've got to kind of look at each

1:37.3

individual label, each individual brand name. And I will say our friends at pearls.com have a wonderful resource with all the brand names,

1:47.4

and I certainly didn't list them all in the podcast here.

1:51.0

So to do that, you can go check out pearls.com slash rlp, like real-life pharmacology.com.

1:59.5

Simply creating a free account there, you'll get access to their layout, their PDF,

2:06.2

of all the different birth control options, brand names,

2:12.2

and what the different strength and dosage forms are there.

2:15.4

So a great resource.

2:16.9

I used it to help kind of put this together a little bit as well.

2:21.0

So let's get into mechanism of action a little bit.

2:26.1

Estrogen, so ethanol estradial is basically estrogen.

...

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