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Emergency Medicine Cases

Episode 89 – DOACs Part 2: Bleeding and Reversal Agents

Emergency Medicine Cases

Dr. Anton Helman

Education, Health & Fitness, Courses, Medicine, Science

4.7602 Ratings

🗓️ 6 December 2016

⏱️ 54 minutes

🧾️ Download transcript

Summary

In this Part 2, DOACs Bleeding and Reversal we discuss the management of bleeding in patients taking DOACs with minor risk bleeds, like epistaxis where local control is easy to access, moderate risk bleeds, like stable GI bleeds and high risk bleeds, like intracranial hemorrhage. We answer questions such as: How do we weigh the risks and benefits of stopping the DOAC? When is reversal of the DOAC is advised? How best do we accomplish the reversal of DOACs? Is there any good evidence for the newest reversal agent? When should we stop DOACs for different procedures, and when should we delay the procedure?

Transcript

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0:00.0

Welcome to the Emergency Medicine Cases podcast.

0:05.8

I'm your host, Dr. Anton Hellman, bringing you Canada's brightest minds in emergency medicine

0:10.5

from EMC studios in Toronto.

0:14.0

In part one on DOAC's use and misuse, we talked about how DOACs work, their efficacy and safety

0:19.8

compared to warfarin, how to dose them,

0:22.4

and when to avoid them. We also covered isolated calf DVT, superficial vein thrombosis,

0:28.0

and anticoagulation in a fib. In this part two, doaxin bleeding, we're going to go through

0:34.4

a few cases showing the range of risk of badness in patients bleeding on DOACs.

0:40.4

We see this all the time.

0:42.9

So from minor risk like epistaxis, where local control is easy to access, to moderate risk like a stable GI bleeder, to major risk,

0:52.3

bleeding into a closed fixed space like ICH.

0:56.0

In each of these cases, we'll discuss how to weigh the risks and benefits of stopping the DOAC,

1:02.4

when reversal the DOAC is advised, and how best to accomplish the reversal.

1:06.9

We'll have an EBM bottom line on the evidence for the newest reversal agent, and we'll discuss when we should and should not stop DOACs for different procedures.

1:16.4

Now, before we jump into the first case, apologies for those of you who couldn't get a spot for the sold-out 2017 EM cases course.

1:23.9

We'll be thinking about maybe expanding the course a bit for the following year.

1:28.8

Another great case-based course that I'll be speaking at is Whistler's update in EM at the end

1:34.3

of February with EM case's guest experts, Chris Hicks, Joel Yaffe, Eric Latofsky, Anil Chopra,

1:41.7

Aaron Ciel, the brains behind the amazing casted course, who, by the way, we're going to have on the show soon.

1:48.6

Sarah Gray, Jason Fisher, and Dave McKinnon.

1:53.0

All right, let's get into Doaxon bleeding.

1:56.1

Here's case number one.

...

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