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The Science of Everything Podcast

Episode 72: Introduction to the Immune System Part 1

The Science of Everything Podcast

James Fodor

Social Sciences, Natural Sciences, Science

4.8819 Ratings

🗓️ 27 February 2015

⏱️ 55 minutes

🧾️ Download transcript

Summary

An overview of the human immune system, beginning with some basic anatomy of the lymphatic system, and proceeding through a discussion of the distinction between the innate and adaptive immune systems, the role of skin and mucus membranes in providing barriers to pathogen entry, the inflammatory response, an overview of the different types of leukocytes, and an initial foray into the workings of the complement system. Recommended pre-listening is Episode 10: The Cell.

Transcript

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0:00.0

Oh, wow, oh, oh, wow, oh, wow, oh, wow.

0:13.0

Oh, wow.

0:15.0

Oh, yeah. Hello, you're listening to the Science of Everything podcast episode 72, introduction to the immune system, part one.

0:41.5

And I'm your host, James Fodor. So in this episode, we're going to start looking at the immune system and immunology,

0:48.0

and we won't get through it all today, so hopefully we'll be able to fit it into maybe two episodes and three at the most,

0:56.3

but we'll see how we go.

0:57.7

So in this series of shows, what we'll look at first is the basic anatomy of the immune system,

1:04.5

so we'll look at the lymphatic system and the primary and peripheral lymphoid organs,

1:08.5

and then we'll move on to looking at all of the different types of, or major different types of cells that are active in the immune system, they're

1:16.4

called leukocytes. So we'll look at neutrophils, and acinophils, basophiles, lymphocytes,

1:21.9

monocytes, and the different types of those. We'll also look at other processes involved in the immune system like

1:29.3

mucous, membranes, inflammation, the skin as a barrier. We'll talk about the complement system,

1:36.3

cytokines, we'll talk about antibodies and antigens, and being in T cells and how they form

1:41.2

the adaptive immune system. And if we have time, we may also at at the end, look, talk a little bit about agglutination

1:47.3

and some aspects of seriology.

1:49.5

So that's basically testing blood samples for the presence of particular antigens.

1:54.3

So basically, the structure of this series of episodes are we trying to understand how

1:59.9

the immune system works and how all the different bits fit together, because it's quite a complicated system.

2:04.3

So we'll try and peel away the complexity and try and explain it in a way that hopefully

2:08.5

makes at least a little bit of sense.

2:11.1

No particular prerequisite episodes for this, although it would help if you had a little

2:15.8

bit of basic background of, say, cellular biology.

...

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