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Newt's World

Episode 509: New Alzheimer's Disease Treatment – LEQEMBI

Newt's World

Gingrich 360

News, Politics

4.66.4K Ratings

🗓️ 14 January 2023

⏱️ 18 minutes

🧾️ Download transcript

Summary

Eisai Co., Ltd. and Biogen Inc. announced on January 6th that under the Accelerated Approval Pathway the U.S. Food and Drug Administration (FDA) has approved lecanemab-irmb, which has the brand name in the United States of LEQEMBITM, for the treatment of Alzheimer’s disease.  The approval is based on Phase 2 data that demonstrated that LEQEMBI reduced the accumulation of Aβ plaque in the brain, a defining feature of Alzheimer’s disease.  Newt’s guest is Dr. Marwan Sabbagh, MD.  He is a behavioral neurologist in the Alzheimer’s and Memory Disorders Program and a professor in the Department of Neurology at Barrow Neurological Institute and was one of the leading doctors of the study.

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Transcript

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0:00.0

On this episode of Newsworld, SA Company and Biogen announced on January 6th that under

0:10.2

the accelerated approval pathway, the US Food and Drug Administration FDA has approved

0:16.2

Lecannamaib IRMB, which has the brand name in the US Lecquembee for the treatment of

0:21.6

Alzheimer's disease.

0:23.2

The approval is based on phase 2 data to demonstrate that Lecquembee reduced the accumulation

0:28.3

of plaque in the brain a defining feature of Alzheimer's disease.

0:33.4

Using the recently published data from the large global confirmatory phase 3 clinical

0:37.6

trial, Clarity AD, SA will work quickly to file a supplemental biologics license application

0:44.8

to the FDA for approval under the traditional pathway.

0:48.2

Here to talk about this remarkable breakthrough for Alzheimer's disease treatment, I am really

0:53.2

pleased to welcome my guest, Dr. Marwan Sabah, who I first worked with back in 2008.

0:59.2

He is a behavioral neurologist in the Alzheimer's and Memory Disorders Program and a professor

1:04.9

in the Department of Neurology at Barrow Neurological Institute and is one of the leading doctors

1:09.5

on the study.

1:13.0

Marwan, thank you for joining me on Newsworld.

1:22.2

I am glad you are still passionate about Alzheimer's.

1:26.8

What led you to have such a deep passion of interest in Alzheimer's and dementia?

1:31.6

Yes, so I did not run in my family.

1:34.4

I had a fear of getting old and I thought that Alzheimer's was the embodiment of everything

1:39.4

sad and destructive about getting old.

1:42.0

Fortunately I have been cured of that.

1:43.3

I am very optimistic about the future of aging, the future of Alzheimer's and so that is

...

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