Episode 463: Insulin, Leptin, and Cortisol: The Triple Threat to Metabolic Success

Naturally Nourished

Ali Miller RD

Nutrition, Health & Fitness:nutrition, Health & Fitness

4.7 • 668 Ratings

🗓️ 29 September 2025

⏱️ 49 minutes

🔗️ Recording | iTunes | RSS

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Summary

In this episode of the Naturally Nourished Podcast, we focus on three key hormones that can significantly impact metabolism: insulin, leptin, and cortisol. Each of these hormones plays an essential role in regulating energy, hunger, and stress, and when imbalances occur, they may be the underlying cause of a metabolic stall or plateau. The conversation explores how insulin resistance can block fat burn, how leptin resistance can interfere with satiety signals, and how cortisol dysregulation can drive cravings and fat storage. We discuss practical strategies for identifying when these hormones are out of balance, along with food-as-medicine approaches, lifestyle modifications, and targeted supplementation to help restore harmony and support optimal metabolic function. Also in this episode: Join our Keto Reset Program Naturally Nourished Kids Book Tour Events Insulin Naturally Nourished Episode 459 Why Insulin Matters Improved Skeletal Muscle Insulin Sensitivity Study Rapid Reduction in Insulin Resistance Markers Study Leptin Naturally Nourished Episode 146 Keto as a Hormetic Stressor and Leptin Naturally Nourished Episode 356 Low Fat Keto for Leptin Resistance What is Leptin and why it matters High vs. Low Leptin Leptin, Obesity, and Leptin Resistance: Where Are We 25 Years Later? Ideal range for leptin 5-10 Cortisol Metabolic and blood sugar impact The Anti-Anxiety Diet Adrenal Rehab Program Calm and Clear Relax and Regulate Adaptogen Boost How a Keto Reset Supports Insulin, Leptin & Cortisol Regulation This episode is sponsored by: According to extensive research by the Environmental Working Group, virtually every home in America has harmful contaminants in its tap water. That’s why you’ve got to check out AquaTru. AquaTru purifiers use a 4-stage reverse osmosis purification process, and their countertop purifiers work with NO installation or plumbing. It removes 15x more contaminants than ordinary pitcher filters and are specifically designed to combat chemicals like PFAS in your water supply. Naturally Nourished Podcast listeners can use code ALIMILLERRD at AquaTru.com to save 20% off.

Transcript

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0:00.0	Welcome to the Naturally Nourished Podcast that delivers cutting-edge food is medicine solutions for optimal health.
0:12.8	Ali Miller is a nutrition expert sought up by the media in America's top medical institutes
0:18.3	for her revolutionary functional medicine interventions.
0:22.6	From disease treatment to prevention, every episode will empower you with ways to put yourself
0:28.3	back in control of your health. Please know, the topics discussed are for educational purposes
0:35.1	only. Now welcome, Integrative Dietitians, Allie Miller, and her co-host Becky You.
0:42.2	Welcome to episode 463 of the Naturally Nourished Podcast.
0:46.9	Last week, we launched our keto reset program, and we're already starting to see some momentum
0:53.0	and positive results. So we wanted to get on
0:56.2	here and talk about three key hormones that can disrupt your metabolism. We're talking about insulin,
1:03.1	leptin, and cortisol. And all three of these hormones when imbalance can be the driving cause of
1:09.2	metabolic stall or handicap.
1:12.1	Yes, I think that we have really done a deep dive on each of these independent,
1:17.7	and we'll share some great podcast archives as we unpack insulin, leptin, and cortisol.
1:23.8	But all too often, I see a little bit of all of them coming into play and this especially can be
1:30.7	exacerbated with mismanaged stress or high demands taking on too much not editing our task
1:37.7	list and we can find ourselves without satisfaction at meal time dealing with hunger middle, middle of the night waking, stubborn belly
1:46.6	fat, hormone imbalance, and so much more. So today we're going to unpack each of these areas,
1:52.6	how they impact your metabolism, how to test or assess them, and then of course lifestyle and
1:57.9	supplement support to regulate so that you can really unlock your stubborn metabolism
2:03.5	for good. Okay. So for those who missed maybe the first week, we still do have a few spots
2:11.1	available in our keto reset program. And we're allowing folks to join through week three. Is that
	...

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