Hey, folks, just a quick reminder that this podcast is not meant to be used for medical advice,

just good old-fashioned education.

All right, welcome back clinical problem solvers.

Our first case is by Dr. Anand Patel from

you Chicago, Hemunk, and it's the case of a 52-year-old man presenting with fevers and malaise.

He's had 12 days of fevers and subjective malaise without a clear pattern to the fevers.

His T-Max at home was 102.6, and he's been alternating ibuprofen and acetaminophen without

improvement in the fevers or symptoms. In the same time, he's also been noting anorexia

and night sweats, but without any other localizing infectious symptoms. In social history,

he lets you know that he frequently does yard work. Ooh, what a start.

Fever and night sweats?

Oh, Hannah, you're too kind.

I feel badly for saying that, partly because I would be miserable if I were this patient,

but certainly an interesting thing to think about.

So I'm going to just tackle speaking about fevers in general and then use resa's help to help us layer

on some clues for this specific patient. And when someone's febrile, you know, I kind of just

take the liberty of translating that into inflammation. And as we've said before on the podcast,

really the goal with inflammation is to figure out two things. One, what is the nature of the

inflammation? Is it

infectious, autoimmune, malignant, and then other, with the other being a catchment for many

other things that can cause a fever, but those are the three priorities that I think of. So what is the

nature of the inflammation? And two, where is it coming from? And it's those two questions that we try to answer, prioritizing infection, primarily because

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