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The Science of Everything Podcast

Episode 18: Biochemistry Basics

The Science of Everything Podcast

James Fodor

Social Sciences, Natural Sciences, Science

4.8819 Ratings

🗓️ 20 June 2011

⏱️ 46 minutes

🧾️ Download transcript

Summary

An overview of biochemistry, covering the basic properties, structure and functions of nucleic acids, lipids, carbohydrates and proteins. Also includes a discussion of the nature of organic molecules and the importance of carbon in living organisms. Recommended pre-listening is Episode 15: Chemical Bonding.

Transcript

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0:00.0

Oh, wow, oh, oh, oh, wow, oh, oh, wow.

0:13.0

Oh, wow.

0:15.0

Oh, my. Hello, you're listening to The Science of Everything podcast, episode 18,

0:39.3

Biochemistry basics.

0:44.1

So in today's episode, I'm going to talk about the basic principles of biochemistry,

0:49.1

which is the chemistry of living things and organic molecules.

0:52.2

And I'm going to talk about in particular the basic properties,

0:56.0

structure, and functions of the four main classes of bioorganic molecules, which are proteins, nucleic acids, lipids and carbohydrates.

1:02.0

And before I do that though, I'm going to give a brief outline of what organic molecules are

1:06.0

and why they're so important in living organisms and just generally about what biochemistry is about.

1:11.6

So biochemistry is kind of the foundational field for the study of biology,

1:16.6

because to understand biology, you have to understand cells, because every living thing is made up of cells,

1:21.6

and to understand cells, you have to understand the molecules from which they are made,

1:26.6

and those molecules are

1:28.2

biomolecules, and the study of those biomolecules is biochemistry. All organic molecules are made

1:34.7

from carbon, and carbon is, therefore in a sense, the building block of life. Everything that we

1:40.8

know that is alive is made largely from carbon, covalently bonded to atoms of hydrogen, oxygen, sulfur, nitrogen, a few other elements nearby on the periodic table.

1:50.9

Carbon is a relatively rare element in the natural world. It only accounts for 0.03% of the Earth's total crust, but it accounts for almost 20% of the total mass of a human body. So carbon is substantially

2:03.6

concentrated and well ever represented in terms of mass in living creatures. So why is carbon so important?

2:10.6

The reason is because carbon has four valence electrons, that is it has four electrons in its outermost shell, and that outermost shell has a capacity of eight. So four valence electrons. That is, it has four electrons in its outermost shell, and that

2:17.9

outermost shell has a capacity of eight. So, four valence electrons provides the largest number of

2:22.6

bonding opportunities, because, as mentioned in the previous episode, atoms tend to fill up

...

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