Oh, wow, oh, oh, oh, wow, oh, oh, wow.

Oh, wow.

Oh, James. Hello, you're listening to The Science of Everything podcast, episode 117, intracellular protein sorting.

I'm your host, James Fodor.

So this episode continues on from the previous episode, 116, the cell membrane.

And here we're talking about the cell membrane in the intracellular context.

So specifically, that means we're going to be looking at the endomebrane

system, the system of membranes inside the cell, and particularly we're going to be looking at

how proteins are sorted and sent to different parts of the endomebrane system and different organelles

within the cell, and also sent outside of the cell. So we're going to be talking about nuclear transport,

transport to mitochondria

and chloroplasts, as well as organols such as the endoplasmic reticulum, the gall gaparitis, and how

transports vesicles work, moving proteins around different parts of the cell.

Recommended pre-listening is, unsurprisingly, the previous episode, 116 on the cell membrane.

And without further due, then, let's get started and start talking about the endomebrane system. So the endomebrane

system is composed of different membranes that are suspended in the cytoplasm within a eukaryotic

cell. So remember that we've got a double lipid membrane surrounding the entire outside of the cell,

and that's called the plasma membrane.

But the plasma membrane is not just sort of outside the cell.

It's also inside the cell.

Basically, the plasma membrane has bits that are dispersed throughout the interior of the cell,

and that's called the endome membrane system.

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