Welcome to the Fat Emperor podcast. I'm your host, Ivor Cummins. I finally caught up with Gabor Erdozy,

who has extraordinary knowledge on metabolism, immunology, and myriad other vectors of human health.

And we're going to have a fascinating discussion on this current viral issue and cover some of the key aspects.

A lot of people might be still wondering about, including the origins of this nasty little pathogen.

And we do also want to get into the origins of this pathogen and the most probable origins where it came from.

So that'll be very interesting for a lot of people.

But we might start off with insulin resistance, leptin resistance,

and this whole modern massive epidemic of chronic disease driven by that issue.

And there's really two epidemics, at least.

There's the epidemic of that that is

exacerbating massively the epidemic of SARS-CoV-2 so maybe we'll talk for a short

while on on how one is connected to the other yeah last time I think we mentioned

the collision of three epidemics in In fact, I said that it was

the obesity or metabolic disease epidemic, of course the viral epidemic and another one I suggested

was vitamin D deficiency as kind of a third epidemic.

So it's a combination or collision of three different problems.

There are different hypotheses about what exactly causes the interference between obesity or metabolic diseases and COVID-19.

I think what I tend to buy into, after looking into a lot of details and mechanistic research,

is that this virus can specifically bind a toll-like receptor,

which is called TLR, the TLR-like receptor abbreviation, TLR4,

and this receptor is kind of over-activated in people with metabolic diseases already. So they have this metabolic inflammation

going on, a lower grade of inflammation, but chronic inflammation going on in their bodies.

...