Today, I am delighted to reconnect with my friend and colleague, Dr. Amy B. Killen, a board-certified physician with expertise in bioidentical hormones, personalized medication, and cutting-edge rejuvenation techniques. In our conversation, we dive into the spectrum of progesterone sensitivity, exploring why estrogen is considered the best longevity drug available and how it reduces the risk of heart disease. We discuss bone health and bioidenticals, outline ways to improve cognition, brain function, and cardiovascular health, and examine the ongoing debate around oral estrogen therapy. Dr. Amy also sheds light on slowing ovarian aging, explains the concept of hair pause and how to address it proactively, and offers her take on overrated or ineffective strategies for navigating perimenopause and beyond. You will not want to miss this insightful episode with Dr. Amy Killen, and I look forward to having her back for another conversation. IN THIS EPISODE, YOU WILL LEARN: Dr. Amy sheds light on the spectrum of progesterone sensitivity. Progesterone treatment options for women with progesterone sensitivity Why estrogen is crucial for longevity How estrogen protects the heart and blood vessels, reducing the risk of cardiovascular disease When is the best time to start taking estrogen for optimal cardiovascular benefits? Estrogen and bone strength and flexibility Can starting estrogen treatments early help prevent dementia and cognitive decline? Pros and cons of using a combination of estriol and estradiol Slow ovarian senescence and prevent hormonal changes from affecting your hair health. Bio: Dr. Amy B. Killen, M.D., is a leading physician in regenerative and hormone optimization medicine, specializing in women's health and helping patients navigate their "Queen PhaseTM" with evidence-based interventions. As a board-certified emergency physician turned longevity specialist, she combines cutting-edge treatments, such as stem cell therapy, hormone optimization, and peptides, with practical lifestyle wisdom at her clinics in Utah and Texas, while sharing her expertise through international speaking engagements and educational content creation. Dr. Killen is the Chief Medical Officer of Humanaut Health, a longevity clinic franchise, and founder of the Human Optimization Project (HOP), a female-focused supplement company. She lives in Salt Lake City with her family of five. Connect with Cynthia Thurlow   Follow on Twitter Instagram LinkedIn Check out Cynthia’s website Submit your questions to [email protected] Connect with Dr. Amy Killen On her website HopBox (Supplement Company) Subscribe to Dr. Amy’s Substack