Ep. 302 - Breaking: 4 Hidden Types of Insulin Resistance Revealed | Personalized Fasting Strategy Based on Your Metabolic Subtype | Why One-Size-Fits-All Fasting Fails | Stanford Research Decoded | New Fasting Persona Quiz!

Fasting For Life

Scott Watier

Nutrition, Alternative Health, Health & Fitness

4.6 • 1.1K Ratings

🗓️ 14 October 2025

⏱️ 48 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

This groundbreaking episode unveils Stanford Professor Michael Snyder's revolutionary research published in Nature Biomedical Engineering revealing that type 2 diabetes and insulin resistance aren't single diseases but four distinct metabolic subtypes requiring personalized fasting and nutrition strategies. The hosts decode how muscle insulin resistance demands early time-restricted eating with 18:6 or OMAD plus resistance training, beta cell dysfunction requires gentle 16:8 fasting while avoiding extended fasts to prevent pancreatic burnout, impaired incretin effect needs pre-meal walking with fermented foods to enhance gut hormone signaling, and liver glucose dysregulation necessitates 30-36 hour fasts weekly to reset hepatic insulin resistance and stop the liver's continuous glucose output. Dr. Scott and Tommy explain why A1C measurements provide almost no insight into underlying mechanisms, with individuals showing normal A1C yet severe insulin resistance while others display pre-diabetic A1C with preserved insulin sensitivity, making traditional one-size-fits-all weight loss recommendations fundamentally flawed. The episode introduces at-home oral glucose tolerance testing to decode personal glucose curves and identify specific pathology, while emphasizing foundational recommendations—early meals, resistance training, post-meal walks, protein prioritization, sleep protection, and stress management—move the needle for most people regardless of subtype, with personalized optimization becoming critical for those stuck despite consistent effort. ⁠⁠⁠⁠⁠Take the NEW FASTING PERSONA QUIZ! - The Key to Unlocking Sustainable Weight Loss With Fasting!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Resources and Downloads: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SIGN UP FOR THE DROP OF THE ULTIMATE GUIDE TO BLOOD SUGAR CONTROL⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠GRAB THE OPTIMAL RANGES FOR LAB WORK HERE! - NEW RESOURCE! ⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠FREE RESOURCE - DOWNLOAD THE NEW BLUEPRINT TO FASTING FOR FAT LOSS!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠SLEEP GUIDE DIRECT DOWNLOAD⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠DOWNLOAD THE FASTING TRANSFORMATION JOURNAL HERE!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Partner Links: Get your⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ FREE BOX OF LMNT⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ here!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Get ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠25% off a Keto-Mojo⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ blood glucose and ketone monitor (discount shown at checkout)! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Click here!⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Our Community: Let’s continue the conversation. Click the link below to JOIN the ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fasting For Life Community⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply! If you enjoy the podcast, please tap the stars below and consider leaving a short review on Apple Podcasts/iTunes. It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them! Article Links: https://www.nature.com/articles/s41551-024-01311-6

Transcript

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0:00.0	Hello, I'm Dr. Scott Wadier.
0:03.0	And I'm Tommy Welling, and you're listening to the Fasting for Life podcast.
0:07.0	This podcast is about using fasting as a tool to regain your health, achieve ultimate wellness, and live the life you truly deserve.
0:15.0	Each episode is a short conversation on a single topic with immediate actionable steps.
0:20.0	We cover everything
0:21.2	from fat loss and health and wellness to the science of lifestyle design. We started fasting
0:25.9	for life because of how fasting has transformed our lives and we hope to share the tools
0:30.0	that we have learned along the way.
0:31.6	Hey everyone, welcome to the Fasting for Life podcast. My name is Dr. Scott Water, and I'm here, as always, I'm a good friend and colleague, Tommy Welling. Good afternoon to you, sir.
0:47.3	Hey, Scott. How are you? Doing fantastic, my friend. Excited for today's conversation. It is an absolute doozy. This is one that we're going to be
0:56.6	unpacking over the next few weeks to months to develop some tangible tools and guides on how
1:03.5	we can implement this groundbreaking research into your fasting lifestyle. So we are going to nerd out
1:09.0	a little bit, but most importantly, we're going to
1:11.8	explain it in a way that allows you to identify and then take action based on where you are
1:17.7	in your fasting lifestyle journey. Ultimately, if you're new to the podcast, you hear it probably
1:22.6	because you want to lose some weight. Get healthy once and for all. Get off that diet roller coaster.
1:28.4	So welcome in.
1:33.1	We are so happy you're here with us. If you want to know more about Tommy's journey, my journey,
1:38.3	why we do what we do week and week out, head back to episode zero and episode one. Give it a quick listen. That'll give you some insights into how fasting transformed our lives and now why we just
1:43.6	passed 300 million, 300 million,
1:47.3	300 episodes nearing 5 million downloads.
1:51.6	Yeah, wow.
	...

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