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This Podcast Will Kill You

Ep 176 Strychnine: The WD-40 of Victorian Medicine

This Podcast Will Kill You

Exactly Right and iHeartPodcasts

Health & Fitness, Science

4.817.1K Ratings

🗓️ 20 May 2025

⏱️ 80 minutes

🧾️ Download transcript

Summary

This week, we’re coming at you with a classic TPWKY episode on one of the most notorious poisons out there: strychnine. Although strychnine might not flash across too many headlines these days, it was once imported by the ton in certain regions of the world. What did people want with so much strychnine? Depends on who you ask. Maybe it was for a revitalizing tonic, maybe a rat poison, or maybe it was to murder the founder of a famous university. Tune in to learn how this deadly poison acts on the body and keep listening for a very special musical treat. 

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Transcript

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0:00.0

This is exactly right.

0:05.9

In January 1893, it happened that I had for a few weeks been in the habit of taking an occasional

0:13.0

dose of one of our stock dispensary mixtures, a tonic containing, amongst other things,

0:18.9

a fair dose of strychnine. On the morning of Tuesday, January

0:23.6

10th, I went into the dispensary to take a dose of the tonic. I at once noticed a much more intensely

0:30.4

bitter taste than was usual. I did not know quite what to do, and my first impulse was to take an

0:36.4

emetic. But as the swallowing of saliva

0:39.6

lessened the bitter taste every minute that I hesitated, I persuaded myself that the difference

0:44.8

might only be fancy. Fifteen minutes elapsed, and I began to feel very restless. An indescribable

0:52.9

nervous sensation came over me, as if there were rope pullies

0:56.6

running down to my extremities, which were gradually being drawn tight. I had to make an effort to

1:02.6

prevent my mouth closing too soon as I spoke, and to dig my pen into the paper and write thick

1:08.2

as if to form a fulcrum over which to lever my hand along the pages,

1:12.5

while a contra force in my arm strove to dash the pen to the floor. My limbs were throwing off the

1:18.1

control of will and moved erratically. When I wished to go on, my legs stopped. And when by a violent

1:25.6

effort I forced them to proceed, I could not pull up to a standstill

1:30.1

without walking against a bed to steady myself. What I said or did, I cannot remember, but I managed to

1:37.4

get along somehow, though feeling as if head, hands, and legs belonged not to me, but to three

1:44.0

separated individuals, like a mechanical

1:46.6

doll that has had all its limbs pulled with a jerk of the string.

1:51.3

I said to Dr. Considine, I am really very ill. I feel sure I am suffering from strychnine poisoning.

1:58.8

I had taken six-tenth of a grain. I remembered that half a

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