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Finding Genius Podcast

Engineering a Virus that Infects Tumors: Dr. Tony Reid and the Cancer-Fighting Work of EpicentRx

Finding Genius Podcast

Richard Jacobs

Medicine, Health & Fitness

4.41K Ratings

🗓️ 5 May 2020

⏱️ 31 minutes

🧾️ Download transcript

Summary

Dr. Reid is Chief Scientific Officer and President of EpicentRx and discusses their groundbreaking work.

He explains

  • How viruses typically seek out specific cell types,
  • How researchers at EpicentRx were able to engineer a virus to seek out cancer cells for infection, and
  • When the public will be able to utilize this antitumor activity to fight cancer.

Dr. Tony Reid obtained his PhD in biochemistry and his MD at Stanford and actually built the foundation of his present work during his graduate efforts there. He begins by explaining how viruses work. For example, adenoviruses have various manifestations that target certain cell types such as lung or gut cells.

EpicentRx has taken that characteristic and engineered a virus to attack and kill cancer cells without harming other bodily cells. In addition, the virus alters the immune system so other cancer cells can be seen and treated effectively. Rather than using virus research to create antiviral medication, they've used it to create anticancer medication.

Dr. Reid explains the process more closely, how after detecting molecular switches that told a virus to infect lung tissue, they knocked that signal out so it wouldn't be able to infect lung tissue, and ended up with a weakened virus. They went in and sequenced the virus and made very small, deliberate changes so it would infect cancer cells.

He discusses the intricacies in more detail, the studies they've done, and says they've already gotten FDA approval and hope to release the medication and engage in antitumor activity this year. 

He finishes by addressing the coronavirus and says his company is actually working on an antiviral medication, more specifically a vaccine that will be successful for the general public but also for immune-suppressed and compromised individuals such as cancer patients. 

For more, see the company's website at http://www.epicentrx.com/.

Transcript

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0:00.0

Forget frequently asked questions.

0:02.0

Common sense, common knowledge, or Google.

0:05.0

How about advice from a real genius?

0:07.0

95% of people in any profession are good enough to be qualified and licensed.

0:11.0

5% go above and beyond. They become very good at what they do, but only 0.1% are real Jesus.

0:18.0

Richard Jacobs has made it his life's mission to find them for you. He hunts down and interviews geniuses in every field, sleep science,

0:25.7

cancer, stem cells, ketogenic diets, and more. Here come the geniuses. This is the Finding Genius

0:32.1

podcast that Richard Jacobs. This is the Finding Genius Podcast.

0:33.0

That is Richard Jacobs.

0:35.0

Hello, this is Richard Jacobs with the Finding Genius Podcast.

0:41.0

My goal, as usual, is to find exceptional people, you know, clinicians, researchers, doctors, etc.

0:47.0

I interview them and hopefully asking good questions where I get information out of them

0:52.0

they don't normally provide and you know boring articles

0:55.1

and you know in the news I want to get to the deep stuff so today I have Dr Tony Reed he's

1:01.0

an epicent or X he's the chief scientific officer. He has a PhD that was focused on

1:06.5

antiviral and anti-tumor activity from Stanford. So we're going to talk about his work at

1:12.0

Epicicent Rx.

1:13.0

So, Tony, thanks for coming.

1:15.0

Thanks.

1:16.0

So just for, just to help you out, the company is Epicentrics.

1:22.0

Oh, no, I, for listeners, I, my kids make fun of me with my pronunciation and whenever

1:27.3

this compound words like that or compound things, I mispronounce them, so everyone does it's you wouldn't you

...

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