Endometriosis 101: Why Gut Health, Histamines, and Toxins Matter | Ep 366

The Funk'tional Nutrition Podcast

Erin Holt

Mental Health, Health & Fitness, Alternative Health, Nutrition

4.9 • 759 Ratings

🗓️ 24 June 2025

⏱️ 28 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

If you've ever been told that endometriosis is “just a hormonal issue”, this episode will challenge everything you thought you knew. Endo is not a simple diagnosis - it’s a whole body inflammatory disease, and conventional approaches often miss key contributors like gut dysbiosis, immune dysfunction, and histamine intolerance. Through powerful client case studies, Erin highlights how a root cause lens can bring real relief where protocols alone fall short.

You’ll learn how functional testing like stool analysis, SIBO breath tests, and even mold and toxin panels can uncover what's really going on beneath your symptoms. Whether you’ve been living with endo symptoms for years or are just starting your healing journey, this episode will help you reclaim your health.

In this episode:

Why up to 90% of people with endo ALSO struggle with irritable bowel symptoms
How LPS-producing bacteria and gut imbalances can drive immune dysfunction in endometriosis
The connection between estrogen, histamine, and mast cell activation (and why it matters for symptom relief)
What high beta-glucuronidase on a stool test could tell you about hormone detox pathways
When it’s time to look beyond gut and hormone tests and look to mold, toxins, and deeper functional markers

Transcript

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0:00.0	Endo is really a whole body inflammatory disease. There is immune dysfunction associated with endometriosis.
0:08.7	Whether or not endo should be considered in autoimmune disease itself is pretty controversial.
0:17.1	We know that there's a lot of inflammation and we know that there's some immune involvement
0:21.2	in endometriosis. And because of that, there's multiple factors that can contribute to the
0:28.3	overarching immune dysregulation and inflammation that is associated with endometriosis.
0:33.2	Welcome to the functional nutrition podcast, spell it with a K, because we do things a little
0:37.0	differently around here. I'm your host, Erin Holt, and I've got 15 years of clinical experience
0:41.7	as a functional nutritionist and mindset coach, creating a new model that I call intuitive
0:46.4	functional medicine, where we combine root cause medicine with the innate intelligence of your
0:51.4	body. This is where science meets self-trust. Your body already knows how to
0:56.5	heal and this show is going to show you how. If you're looking for new ways of thinking about
1:01.2	your health, be sure to follow and share with a friend because you never know whose life you might
1:05.4	change. Hello out there. I hope everyone has enjoyed your June so far. I'm gearing up, getting ready to head up to the lake for a good chunk of the summer. So I am getting ahead of all the podcast content. So I don't leave you with a big gap, you know, an entire summer without podcasting. I don't think so. So I've got good stuff coming
1:29.2	your way. Today is really focused on endometriosis. A recent conversation with a friend
1:34.7	about endometriosis really inspired me to create this episode. We were talking about stuff
1:40.6	more from a marketing perspective, talking about complex cases. And I was explaining to her how
1:46.6	we often work with people who have struggled for a long time, probably years with symptoms,
1:53.6	have worked with multiple practitioners by the time they get to us. But I was saying that I don't
1:59.2	necessarily want that to be the most prominent,
2:02.1	forward-facing marketing. Like, hey, are you a total mess? We can help. Not everybody sees
2:09.3	themselves as a complex case. And she was like, yeah, totally. That would leave me out because
2:14.8	I just have endometriosis. That's my only diagnosis. That's all I have.
	...

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