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Science Quickly

ENCORE: Science’s Greatest 180s

Science Quickly

Scientific American

Science

4.41.4K Ratings

🗓️ 29 December 2025

⏱️ 5 minutes

🧾️ Download transcript

Summary

Science doesn’t always get it right the first time—and that’s part of the journey. In this anniversary special, we explore how ideas about nerve damage, sustainable materials and alien life have done a full 180. This episode first aired in August. Recommended Reading Celebrating 180 Years of Scientific American 180 Years of Standing Up for Science How Scientists Finally Learned That Nerves Regrow Proof That Adult Brains Make New Neurons Settles Scientific Controversy Plastics Started as a Sustainability Solution. What Went Wrong? The Search for Extraterrestrial Life Is a Roller Coaster of Hope and Disappointment E-mail us at sciencequickly@sciam.com if you have any questions, comments or ideas for stories we should cover! Discover something new everyday: subscribe to Scientific American and sign up for our daily newsletter. Science Quickly is produced by Kendra Pierre-Louis, Fonda Mwangi, Sushmita Pathak and Jeff DelViscio. This episode was edited by Alex Sugiura. Shayna Posses and Aaron Shattuck fact-check our show. Our theme music was composed by Dominic Smith. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

For Scientific American Science Quickly, I'm Kendra Pierloos, in for Rachel Feldman.

0:24.8

This week we're doing something a little different. We're bringing back some of our favorite episodes of the year, starting with our 180th

0:29.1

anniversary special.

0:30.8

A scientific American celebrated the occasion by looking at times in history when science

0:34.6

did an about-face, a complete 180-degree turn.

0:38.7

Moments that had scientists saying, wait, what?

0:41.8

Rachel takes us back in time to some of those unexpected science pivots.

0:45.7

This episode first aired in August.

0:48.8

First up, we have a story from freelance health and life sciences journalist Diana Kwan about

0:54.1

nerve regeneration. For millennia, doctors and scientists believed We have a story from freelance health and life sciences journalist Diana Kwan about nerve

0:54.5

regeneration.

0:56.1

For millennia, doctors and scientists believed that any damage to the nerve cells that

1:00.5

carry signals throughout the body must be irreversible.

1:04.5

While many instances of nerve damage are indeed difficult to treat, scientists have realized

1:09.7

over the past couple of centuries that nerves

1:11.8

can and do regenerate. Throughout this evolution in our understanding of nerves, it was still

1:17.5

widely believed that neurons within the central nervous system, composed of the brain and spinal cord,

1:23.4

were incapable of healing. Now we know that even these most precious neurons can regenerate

1:29.4

under the right conditions. As research continues into exactly which mechanisms encourage or

1:35.3

block neural regeneration throughout the body, scientists are also engaged in another debate,

1:41.3

whether human brains are capable of producing new neurons throughout adulthood.

1:46.1

The phenomenon of adult neurogenesis would have been unfathomable mere decades ago,

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