This is EMKases, EM Quick Hits podcast.

Quick. Let's get on with it.

EM cases is part of Shremie, the Schwartz-Riseman Emergency Medicine Institute.

That's the nonprofit organization dedicated to improving EM care through high-quality research and education. The opinions expressed on this podcast are intended for general information and educational purposes only and should not be used to diagnose treat or prevent any medical condition, nor should they be used as a substitute for medical advice from qualified practicing physician. Unless stated otherwise, the opinions expressed by the hosts or guests are made in their individual capacity, not on behalf of the Institute nor Medicine Cases.

Starting off this month's EM Quick Hits, we've got Ken Milne.

Now, Ken was kind enough to talk at the last EM cases summit, which was in November.

I learned so much there.

My brain almost exploded.

So Ken, who is, of course, the brains behind the S-Gem, I gave him a little challenge, and that was to review the 10 most important papers from 2021 in 10 minutes. Perfect for a

quick hit, right? So here's Ken Milne from the EMCases Summit, 2021.

Hello, I'm Ken Milne, and this is 10 important recent publications in 10 minutes. Let's go.

First paper. There's been a couple of small studies 20 years ago claiming the efficacy of therapeutic hypothermia

and out-of-hospital cardiac arrests. The original targeted temperature management or TTM trial

compared 33 degrees Celsius to 36 degrees Celsius and found no statistical difference.

This new TTM2 trial was a multi-center randomized, unblinded trial of 1900 adult out-of-hospital

cardiac arrest patients who were comatosed and they compared 33 degrees Celsius to keeping

the patient's normothermic.

Key result? No statistical difference in death from any cause at six months. It was about

50% in both groups. Bottom line, we don't need to cool these patients. And I hear there's a

TTM3 trial in the works, which will be normothermia versus

no temperature control. Paper number two. Hyponatremia is the most common electrolyte abnormality

and clinical practice. And we've been warned to correct this slowly to avoid the

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