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Science Quickly

Ebola Virus Grew More Infectious in the Latest Epidemic

Science Quickly

Scientific American

Science

4.2639 Ratings

🗓️ 14 November 2016

⏱️ 2 minutes

🧾️ Download transcript

Summary

A strain that emerged during the latest epidemic is able to enter human cells more easily—which means it’s more infectious, too. Christopher Intagliata reports.  Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

Understanding the human body is a team effort. That's where the Yachtel group comes in.

0:05.8

Researchers at Yachtolt have been delving into the secrets of probiotics for 90 years.

0:11.0

Yacold also partners with nature portfolio to advance gut microbiome science through the global grants for gut health, an investigator-led research program.

0:19.6

To learn more about Yachtolt, visit yawcult.co.j.p.

0:23.9

That's y-A-K-U-L-T dot-C-O-J-P.

0:28.4

When it comes to a guide for your gut, count on Yacolt.

0:33.7

This is Scientific American's 60-second science.

0:37.3

I'm Christopher in Taliatta.

0:39.4

Ebola outbreaks, before the most recent one, have been fairly contained, geographically

0:43.9

limited, and just a couple hundred cases. The latest outbreak, though, which started in late

0:48.7

2013 and lasted more than two years, was entirely different. There were almost 30,000 cases.

0:56.1

Jeremy Lubin, a virologist at the University of Massachusetts Medical School.

1:00.0

You could argue this is the first actual epidemic.

1:03.3

Lubin and his colleagues studied publicly available data on the evolutionary family tree

1:07.5

of the Ebola virus during the latest outbreak, how the strains mutated and changed over

1:12.3

time. And one in particular caught our attention. It arose early in the epidemic, and it's the

1:19.1

only form of the virus that persisted beyond that point. This mutant strain was armed with an

1:25.1

alteration in the protein it uses to enter cells,

1:28.1

and what Lubin's team found was that the modified protein actually made the strain more

1:32.4

infectious to the cells of humans and other primates, but not to other mammals.

1:37.6

The study is in the journal's cell.

1:39.8

Lubin says it's unclear whether this increased infectivity helped drive the outbreak to epidemic proportions,

...

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