Hey, all, welcome back to the Real Life Pharmacology podcast.

I'm your host, pharmacist Eric Christensen.

Thank you so much for taking time on to your day to listen.

Hopefully you pick up a few clinical pearls today.

With that said, I do want to mention real-life Pharmacology.com.

Go snag your free top 200 study guides 31 page PDF simply get it just for

subscribing we send you updates on when we've got new content new podcasts and things of that

nature so definitely go check that out real life pharmacology dot com right, so the drug I wanted to cover today is

du la glutide. And so the brand name of this medication is Trulicity and its medication used in the

management of type 2 diabetes. So mechanistically, this drug does a couple of things. The first thing that I

always remember with the GLP 1 agonis, Dula glutide, is it slows gastric emptying. So two effects that this can lead to is patients may feel a little

bit more full. They may eat a little bit less, which is obviously advantageous in our type 2 diabetes

patients that, you know, in general, most are overweight or a significant majority are

anyway. And then, of course, you're eating less. You're, you know, obviously potentially going

to lower that blood sugar as well through that mechanism. The other primary mechanism that

this drug works through is it helps to secrete insulin and specifically

that after you eat so it helps really lower those blood sugars when blood sugars are elevated so

a couple important mechanisms on how that drug works.

So again, indicated for diabetes can be used in combination with lots of different type 2 diabetes

medications.

I've seen it used in clinical practice used together in all sorts of different combinations.

The one big exception is the DPP4 inhibitors.

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