Drug-Induced Liver Injury (DILI)
Medgeeks with Andrew Reid
Medgeeks
4.8 ā¢ 996 Ratings
šļø 2 October 2023
ā±ļø 11 minutes
šļø Recording | iTunes | RSS
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Summary
In this episode of the Liver Series, Dr. Niket Sonpal discusses drug-induced liver injury (DILI), a common and potentially serious side effect of many medications. DILI can occur in people of all ages, but is more common in older adults and people with pre-existing liver disease.
DILI can be caused by a wide variety of medications, including over-the-counter medications, prescription drugs, and herbal supplements. Some of the most common medications that cause DILI include Tylenol, NSAIDS such as Advil and Aleve.
DILI is usually treated by stopping the medication that is causing the injury. But, in severe cases, the patient may need to be hospitalized.
October 2, 2023
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Transcript
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| 0:00.0 | In health care, every decision has a pro and a con, a positive and a negative. |
| 0:05.4 | Some say the ying and yang, and for the dramatic, like me, we think about good versus evil, |
| 0:11.3 | but that's really just an overstatement. |
| 0:14.0 | For every single intervention, medication we order, we explain to the patients the benefits |
| 0:20.0 | and the risks. |
| 0:21.4 | And many times medications can have untoward side effects that we may not know about. |
| 0:26.8 | And when these side effects happen, it's very disturbing for the health care provider, |
| 0:31.0 | but it's also as equally disturbing and even scary for the patient. |
| 0:36.0 | One such negative outcome are the effects of medications on the liver, known as drug-induced |
| 0:41.5 | liver injury. |
| 0:42.5 | And that's what we're going to be talking about today |
| 0:44.6 | in this week's podcast. |
| 0:46.2 | I'm Dr. Nikit Son Paul, your friendly neighborhood internist |
| 0:48.9 | and gastrantrolyjust, |
| 0:50.1 | and welcome back to the liver series. |
| 0:52.0 | We're going to be talking about Dilly, drug-induced liver injury. It's no surprise we're going to be |
| 1:11.0 | It's no surprise. We're going to be talking about the adverse effects on the liver So many medications get metabolized through it and so many |
| 1:14.6 | medications have good effects. But a lot of things in life have an adverse |
| 1:19.2 | effect or a different use that we may not have known. To give you an idea, let's talk about |
| 1:24.1 | chalk. You know chalk where you write on it on the street and play hopscotch. |
| 1:27.6 | Chalk is actually made of calcium carbonate, which is also a medication. Now, we use it for so many things. |
| 1:34.2 | But did you know that if you heat chalk |
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