Dr. Scott Sherr: Methylene Blue, GABA, and the Hidden Link Between Mitochondria and Stress

The Energy Blueprint Podcast

Ari Whitten

Alternative Health, Health & Fitness

4.6 • 781 Ratings

🗓️ 26 July 2025

⏱️ 58 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

Your mitochondria and responses to stress are more connected than you think.

In this episode, Dr. Scott Sherr is back to tell us about why 94% of US adults have mitochondrial dysfunction and how chronic stress and inflammation deplete GABA, your brain's primary calming neurotransmitter.

We also discuss why methylene blue has exploded from an obscure mitochondrial enhancer to a controversial biohacking trend, how GABA deficiency masquerades as anxiety and depression, and why healing requires shifting from sympathetic dominance to parasympathetic activation.

Dr. Sherr shares his 20 years of clinical experience, demonstrating that within 30 seconds to 2 minutes, he can determine if someone can heal; it all comes down to the state of their nervous system.

Transcript

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0:00.0	Hey, this is Ari. Welcome to the Energy Blueprint podcast with me on the podcast for the third time in seven, eight years, maybe more, is my friend, Dr. Scott Scher, who is a board-certified internal medicine position certified to
0:23.6	practice health optimization medicine. He's also a specialist in hyperbaric oxygen therapy,
0:29.6	and he's the C-O-O of a company called Troscriptions, which we'll talk a bit about in this
0:35.5	podcast. His clinical telepractice includes health optimization
0:39.9	medicine as its foundation, alongside an integrative approach to hyperbaric oxygen therapy that
0:46.0	includes dynamic and cutting edge hyperbaric protocols, comprehensive testing, targeted supplementation,
0:54.0	personal practices, and synergistic technologies,
0:57.6	new, ancient, psychedelic, and much more.
1:01.7	The first podcast that we did many years ago was all about hyperbaric oxygen therapy.
1:08.1	The second one, more recently, maybe a few years ago, was all about
1:13.4	methylene blue. And this podcast starts with sort of an update to the methylene blue story
1:20.8	and some of the different takes that are out there on methylene blue because in the span of time
1:27.2	from the first podcast to now, it's
1:30.1	sort of gone from a fringe thing that very few people knew about to now it's, in a way,
1:35.5	it's kind of mainstream.
1:36.5	It's gotten a lot of public attention.
1:41.0	And then we spend most of the conversation talking about the autonomic nervous system, sympathetic versus parasympathetic, and neurotransmitters.
1:51.7	In particular, a neurotransmitter called GABA.
1:56.1	And why GABA is so important for most modern humans and why so many of us are GABA deficient.
2:03.7	So with no further ado, enjoy this podcast with Dr. Scott Scher. Dr. Scher, welcome back to the show.
2:12.0	It's great to be back with you, Ari. It's been a minute. It has. I think the last time we saw each
2:16.6	other in person, it's got to be six, seven years ago at this point. Oh, yeah, long time. We did a podcast for one of your other podcast channels on Methylene and Blue, maybe about three or four years ago. That's right. And I remember you asking me, Scott, do you think we could do a whole podcast on Methylene Blue? It's like, that's not going to take very long. I'm like, I promise you, it's going to be fine. And we had a great conversation. Yes. Yes. And since that time, methylene Blue has kind of exploded onto the scene. Actually, before, you know, we plan to talk all about GABA in this one, but it might be
	...

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