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PBD Podcast

Dr. Rhonda Patrick: Fasting, Creatine, Brain Performance & Longevity Breakthroughs | PBD #740

PBD Podcast

PBD Podcast

Business

4.44.1K Ratings

🗓️ 17 February 2026

⏱️ 143 minutes

🧾️ Download transcript

Summary

Patrick Bet-David sits down with Dr. Rhonda Patrick to break down biological vs. chronological aging, AI-driven gene therapy and stem-cell breakthroughs, creatine and fasting for brain performance, exercise’s role in reversing heart aging and lowering cancer risk, GLP-1 weight-loss debates, anxiety hacks, and the science behind longevity, family, and happiness.

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ABOUT US:

Patrick Bet-David is the founder and CEO of Valuetainment Media. He is the author of the #1 Wall Street Journal Bestseller “Your Next Five Moves” (Simon & Schuster) and a father of 2 boys and 2 girls. He currently resides in Ft. Lauderdale, Florida.

Transcript

Click on a timestamp to play from that location

0:00.0

I'm 47 years old. I want to feel 30 by the time I'm done talking to you.

0:04.1

The cells in our body have a biological age. And that biological age can be younger if you're

0:09.6

leading a really healthy lifestyle. Or they can be older.

0:11.9

Give me three things you'll say. These are three crazy wild things we may see.

0:15.5

Yeah. So this is where you can basically take this old skin cell and make the cell young. So essentially reversing the aging, but also we can grow organs. Like that's a new thing. So you can basically take someone who has a disease and completely wipe that disease out. It's really kind of cool. It is. Tuning up you can get to a point that people will choose what their kids are going to look like because that's pretty scary if you can get to that point. I mean, that's the ethical question. I mean, what does the world look like in 50, 100 years if we're able to do that? We're living in the shortcut era. Serena Williams, she did a GLP 1 commercial. The average woman looks at that and says, if she couldn't do it naturally, why should I try to do it naturally with exercise? Doing intermittent fasting or counting calories does require effort,

0:57.0

whereas taking a pill does not.

0:58.7

The pill does it for you.

0:59.8

Exercise is the key, and not just any type of exercise.

1:02.2

You have to get your heart rate up.

1:03.4

You have to move faster.

1:05.1

Being sedentary is a disease,

1:06.6

and when you start thinking about it as a disease.

1:08.4

At the end of the day, I'm excited about healthier living.

1:11.6

I'm excited about, you know, yeah.

1:13.4

Yeah.

1:23.0

So it's not often I do an interview, and I take six pages of notes while the guest is speaking,

1:28.3

but that's what happened today with Dr. Rhonda Patrick. Fascinating.

1:32.1

We talked about chemotherapy, the effects of it.

1:34.7

We talked about GLP once.

1:36.7

She reacted to what Oprah Winfrey said a few weeks ago, that being fat is a gene that she has.

1:42.3

It's not her fault.

1:43.1

And her reaction to it was very detailed, very thorough. We talk about diet, exercise, what causes 13 different types of cancer that you have control over, which when you're not going through it, you don't think about it, but if you can prevent it, you may as well. Talk to a lot of different things. What's healthier for you? Being married with kids,

...

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