Dr. Peter Attia: Exercise, Nutrition, Hormones for Vitality & Longevity | Episode 85

Huberman Lab

Scicomm Media

Science, Health & Fitness, Life Sciences

4.8 • 26.2K Ratings

🗓️ 15 August 2022

⏱️ 170 minutes

🔗️ Recording | iTunes | RSS

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Summary

My guest this episode is Dr. Peter Attia, M.D., who trained at Stanford University School of Medicine, Johns Hopkins Hospital and the National Institutes of Health (NIH). Dr. Attia is host of The Drive podcast and is a world expert on behavioral approaches, nutritional interventions, supplementation and pharmacological techniques to improve lifespan, healthspan and athletic performance. We discuss how best to evaluate your health status using routine blood work, body scans and regular tests of physical strength and endurance. Dr. Attia explains what he uses with his patients to “back-cast” their health goals as a way to design their exercise and nutritional programs. We also discuss hormone modulation and replacement therapy for both men and women. We explain how cholesterol and related factors contribute to cardiovascular disease risk and how to monitor and mitigate that risk. Dr. Attia details various supplementation, nutrition, exercise and prescription approaches useful to people in every decade of life to improve vitality, reduce their risk of disease and increase the number of years sustaining peak cognitive and physical health. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://insidetracker.com/huberman Maui Nui: https://mauinuivenison.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Assessing Health Status & Improving Vitality (00:02:51) Momentous Supplements (00:03:46) AG1 (Athletic Greens), InsideTracker, Thesis (00:07:29) Lifespan: Bloodwork & Biomarkers Testing, The “4 Horseman of Disease” (00:11:51) Healthspan: Functional Testing, Cognitive & Emotional States (00:13:59) Blood Testing: Best Frequency (00:16:01) DEXA Scan: Lean Mass & Fat, Bone Mineral Density & Osteoporosis (00:22:33) Bone Mineral Density & Age-Related Decline, Strength Training, Corticosteroids (00:29:24) Osteopenia & Osteoporosis Diagnosis, Strength Training (00:31:03) AG1 (Athletic Greens) (00:32:16) Back-casting: Defining Your “Marginal Decade” (00:38:31) All-Cause Mortality: Smoking, Strength, VO2 max (00:44:43) Attia’s Rule of Supplementation, “Centenarian Decathlete” Physical Goals (00:49:24) Importance of Exercise, Brain Health, MET hours (00:55:23) Nicotine & Cognitive Focus (01:03:12) Menstruation, PMS & Menopause (01:10:10) Hormone Replacement Therapy, Menopause & Breast Cancer Risk (01:22:06) Estrogen, Progesterone & Testosterone Therapies in Women (01:26:35) Hormone Replacement Therapy in Men, SHBG & Testosterone, Insulin (01:37:23) Clomid, Pituitary, Testosterone & Cholesterol, Anastrozole, HCG (01:47:46) Fadogia Agrestis, Supplements, Rapamycin (01:52:06) Testosterone Replacement Therapy & Fertility (01:59:26) Total Testosterone vs. Free Testosterone (02:02:51) Cholesterol & Dietary Cholesterol, Saturated Fat, LDL & HDL, Apolipoprotein B (02:17:42) Apolipoprotein B, Diet, Statins & Other Cholesterol Prescriptions (02:25:15) Cardiovascular Disease, Age & Disease Risk (02:28:53) Peptides, Stem Cells, BPC157, PRP (Platelet-Rich Plasma), Injury Rehabilitation (02:37:40) Metabolomics & Exercise (02:40:44) GLP-1 & Weight Loss (02:47:06) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter, Huberman Lab Clips Title Card Photo Credit: Mike Blabac Disclaimer

Transcript

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0:00.0	Welcome to the Uberman Lab podcast where we discuss science and science-based tools for everyday life.
0:08.8	I'm Andrew Uberman and I'm a professor of neurobiology and
0:12.1	ophthalmology at Stanford School of Medicine. Today my guest is Dr. Peter Atia.
0:17.4	Dr. Atia is a physician who's focused on nutritional, supplementation-based, behavioral,
0:22.9	prescription drug, and other interventions that promote health span and lifespan. His
0:28.1	expertise spans from exercise physiology to sleep physiology, emotional and mental health,
0:34.0	and pharmacology. Today we talk about all those areas of health, starting with the very basic,
0:39.2	such as how to evaluate one's own health status and how to define one's health trajectory.
0:45.6	We also talk about the various sorts of interventions that one can take in order to optimize
0:50.8	vitality while also extending longevity, that is lifespan. Dr. Atia is uniquely qualified
0:57.2	to focus on the complete depth and breadth of topics that we cover. And indeed, these are the
1:02.2	same topics that he works with his patients on in his clinic every day. Dr. Atia earned his
1:07.0	Bachelor of Science in Mechanical Engineering and Applied Mathematics and his MD from Stanford
1:12.1	University School of Medicine. He then went on to train at Johns Hopkins Hospital in General
1:16.9	Surgery, one of the premier hospitals in the world, where he was the recipient of several
1:20.8	prestigious awards, including Resident of the Year. He's been an author on comprehensive
1:25.1	reviews of General Surgery. He spent two years at the National Institutes of Health as a surgical
1:30.3	oncology fellow at the National Cancer Institute, where his work focused on immune-based therapies
1:35.4	for melanoma. In the fields of science and medicine, it is well understood that we are much
1:39.5	the product of our mentors and the mentoring we receive. Dr. Atia has trained with some of the best
1:44.8	and most innovative lipidologist, endocrinologist, gynecologist, sleep physiologist, and longevity
1:49.6	scientists in the United States and Canada. So the expertise that funnels through him and that he
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