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The Bossticks

Dr. Colleen Cutcliffe On How To Naturally Boost GLP-1, Stop Cravings, Fix Bloating, & The Truth About Gut Health

The Bossticks

Dear Media

Education, Business

4.415K Ratings

🗓️ 15 May 2026

⏱️ 55 minutes

🧾️ Download transcript

Summary

#971: Join us as we sit down with Dr. Colleen Cutcliffe – a leading gut microbiome scientist with over 25 years of experience across academia, biotechnology, and pharmaceuticals. As Co-Founder and CEO of Pendulum, she is a trusted voice in gut microbiome science known for translating complex research into clear, actionable insights. In this episode, Dr. Colleen breaks down the latest science behind gut health and its impact on the body – from bloating and metabolic dysfunction to neurological conditions. She also unpacks the risks of counterfeit supplements, what to look for in high-quality products, and how the gut microbiome influences the body's natural GLP-1 production to regulate metabolism, reduce cravings, and support overall health.

 

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This episode is sponsored by Pendulum

Visit http://pendulumlife.com/skinny and use code SKINNY for 20% off your first purchase. 

 

This episode is sponsored by ISWMP

Visit http://istandwithmypack.org to support I Stand With My Pack's (ISWMP) mission by donating or adopting. Every contribution helps!

 

This episode is sponsored by The Skinny Confidential

Upgrade your daily routine with clean beauty and wellness essentials that actually work. Shop now at https://shopskinnyconfidential.com

 

This episode is sponsored by Kindred Bravely

Go to http://kindredbravely.com/SKINNY for 20% off your first order. Exclusion apply. 

 

This episode is sponsored by HERS

Visit http://forhers.com/skinny to get personalized, affordable care that gets you.

 

This episode is sponsored by PVOLVE

Head to http://pvolve.com/skinny and use code SKINNY for 15% off sitewide, or on class packs at a Pvolve studio near you.

 

This episode is sponsored by Woo More Play

To learn more about Woo More Play visit https://woomoreplay.com/discount/skinny and use code SKINNY for 20% off. 


Produced by Dear Media

Transcript

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0:00.0

Welcome to the Bostics, starring Lauren Bostic and Michael Bostick.

0:07.8

Together, they are the Bostics.

0:10.5

We've got a scientist and a gut microbiome expert on the show today.

0:16.2

Please welcome Dr. Colleen Cutcliffe.

0:18.8

She has 25 years of experience advancing biology and human health.

0:24.1

She's a badass. Wow. On this episode, I learned so much about the gut. I was blown away.

0:31.8

She breaks it down in a really clear, credible way. And it's a way that really makes sense. We also talk about some really

0:40.0

interesting topics, like what stimulates the body's natural GLP1 hormone. And we even talk about

0:45.8

improving the metabolism and reducing food cravings. I found this episode fascinating. I know you

0:51.6

will too. With that, let's welcome Dr. Colleen Cutcliffe to the show. We prep for all these things. And a lot of the feedback from the team is like, people are just terrified. They don't know what to do. There's so many illnesses. There's so many new cancers. There's so many things happening as it relates to gut. And people, I mean, you know this. There's a lot of information out of there and people don't know where to turn. They don't

1:11.2

know what to do. They don't know what's real. What's not. So I guess to start, how did you get involved in this space to begin with and how did you get interested in the gut? So I totally agree. It is a really noisy space. Everyone knows, oh, gut health is really important for me. But now what? what do I do? What's actionable from this? And

1:28.5

what is going to help me personally and what's going to help, you know, that person may not be the

1:32.5

same thing. And so for me, I actually didn't really know anything about supplements or probiotics

1:38.9

and things like that. I did all of my research. I have a PhD in biochemistry from Johns Hopkins.

1:43.4

I did a pretty traditional

1:44.7

postdoc at Northwestern. Then I worked as a scientist and a pharma company. We were developing

1:48.9

drugs for Parkinson's disease. Then I worked in a DNA sequencing company doing biology. And so I've had

1:54.1

a really hardcore basic science background. And when I learned about the microbiome, I was like,

2:00.4

wow, this is an entirely new part of our body that we didn't really understand before.

2:03.9

So I came at it from purely a science and almost pharmaceutical kind of an angle and then realized there's a lot of natural things that are happening here and natural ways that we can fix our bodies.

2:14.8

And so we ended up putting our products out as probiotics as opposed to drugs.

2:19.4

But I came to it purely from like a science and clinical and data standpoint. Someone who doesn't

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