4.8 • 877 Ratings
🗓️ 19 March 2025
⏱️ 7 minutes
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0:00.0 | NAD Plus is an essential co-factor for hundreds of enzymes, including the purported anti-eaging |
0:05.8 | activities of CERTuins. In this 10-part video series, I will go through the alphabet soup |
0:12.7 | of NAD boosting supplements on the market, N-R-N-M-N-N-N-H, N-A, N-A-N-A-N-A-N-H and Triptophan. |
0:22.1 | I will then cover the pros and cons of each and discuss three ways to naturally boost NAD levels without supplements. |
0:35.6 | Our understanding of nicotinamide adenine dinuclidid, NAD+, |
0:43.3 | arose from humble beginnings as a factor noted to enhance yeast fermentation in a 1906 paper, unassumingly |
0:51.0 | entitled, the alcoholic ferment of yeast juice. |
0:54.7 | Little did they know that waves of NAD-related discoveries would go on to yield a total of four |
1:00.1 | Nobel Prizes. NAD Plus is now known as an essential molecule for all living organisms |
1:06.1 | required for the function of about 500 enzymes, including, notably, the extraction of metabolic energy |
1:12.2 | from food. |
1:13.8 | The 21st century has produced yet another scientific renaissance for NAD, with the realization |
1:19.2 | that it was critical for the activity of Sertuins, the Guardians of Mammalian Health |
1:23.8 | Span I detail in my book How Not to Age. |
1:31.4 | NAD is one of the most abundant molecules in our body. |
1:36.5 | Once considered relatively stable, it's now known to be in constant state of synthesis, |
1:37.9 | recycling, and breakdown. |
1:43.7 | The entire pool of NAD and some of our tissues is turned over several times a day. To maintain cellular vitality |
1:46.2 | in the face of this turnover, an adequate supply of NAD precursors and sufficiently high enzyme |
1:52.2 | activity synthesizing NAD are critical. The importance of NAD is exemplified by the devastating |
1:59.2 | consequences of a deficiency of NAD precursors like NIA-B3, a deficiency of NAD precursors like |
2:02.4 | niacin, vitamin B3, the deficiency syndrome called Pallegra, is characterized by the 4Ds, |
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