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Big Picture Science

DNA is Not Destiny

Big Picture Science

Big Picture Science

Science, Technology

4.5 • 1K Ratings

🗓️ 8 July 2019

⏱️ 54 minutes

🧾️ Download transcript

Summary

(repeat) Heredity was once thought to be straightforward. Genes were passed in an immutable path from parents to you, and you were stuck – or blessed – with what you got. DNA didn’t change.  But now we know that’s not true.  Epigenetic factors, such as your environment and your lifestyle, control how your genes are expressed. Meanwhile, the powerful tool CRISPR allows us to tinker with the genes themselves. DNA is no longer destiny. Hear the results from the NASA twin study and what happened to astronaut Scott Kelly’s DNA after a year on the International Space Station. Plus, whether there’s evidence that epigenetic changes can be passed down. And, if we can wipe out deadly malaria by engineering the mosquito genome for sterility, should we do it? Guests: Scott Kelly – Former military test pilot and astronaut and author of “Infinite Wonder” Carl Zimmer – Columnist for The New York Times, author of “She Has Her Mother’s Laugh: The Powers, Perversions, and Potential of Heredity" Christopher Mason – Associate professor of genetics and computational biology at Weill Cornell Medicine Michael Snyder – Chair of the genetics department and director of the Center for Genomics and Precision Medicine at Stanford University Nicole Gladish – PhD candidate, department of medical genetics, University of British Columbia Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:56.4

or lowercase. That's Shopify dot co-deekk slash special offer. That's the sound of me consuming a donut and yeah I know it's bad for me all the sugar the fat and so we're it's probably going to add you know a millimeter to my waist within the hour but you know

1:25.8

one thing I never thought it would do and that is modify my DNA although I have to say, even if it does, I'm going to finish this donut.

1:37.0

I'm Seth Shostak.

1:38.0

I'm Molly Bentley.

1:39.0

Welcome to Big Picture Science, produced at the Citi Institute where researchers investigate the nature and origin of life.

1:45.0

On Big Picture Science, we give you the wide-angle view on science and technology.

1:49.0

Herredity was once understood to be straightforward.

1:52.0

Genes were passed from parents to offspring and you were blessed or stuck with the lot you got.

...

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