All right, welcome. My name is Devine. This is episode 128. Of the Devine Intervention

Podcast, in today's podcast, I'm going to be talking about X-Link dominant disorders.

Ex-Linkinant disorders.

This stuff's pretty high you to understand, pretty high you to know.

There are a few excellent-dominant disorders that are pretty important for the USMA exams.

This is a continuation of episode 424 where I talked about some

high-yield roles for remembering modes of inheritance. You should probably go back

and listen to that podcast before jumping into this one.

But if you also just want to understand X-Ling-dominant disorders, this podcast is for you.

So basically what is X-Link dominant inheritance?

Ettling-dominant inheritance is not as common as X-Link recessive.

Many of us are family with X-Link to recessive.

And we talked about in the episode 424 that you know many

immunodeficiency diseases have excellent recessive inheritance because many

genes for the immune system reside on the X chromosome. Now in terms of X-length

dominant inheritance the problem is when you have an affected X chromosome you demonstrate symptoms. There will be a phenotype.

They will be a phenotype. So the dominant gene is carried on the ex-chromosome. So

if you have the bad gene or your ex-chromosome and you have one of you have an

ex-chromosome which every human being has, then the person is going to be affected.

So just having one bad ex-chromosome is sufficient to cause problems.

If you remember in the excellent recessive case, if you have one good ex-chromosome and one bad ex-chrom bad X chromosome you won't have any problems

If you have two bad X chromosomes you will have problems in the X-linked recessive case

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