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» Divine Intervention Podcasts

DIP Ep 596: 2025 USMLE Step 1 Free 120 Discussion Part 11b (Q106-110, super helpful for Step 2 and 3!)

» Divine Intervention Podcasts

Divine-Favour Anene

Science & Medicine, Medicine, Education, Higher Education

4.71K Ratings

🗓️ 25 April 2025

⏱️ 26 minutes

🧾️ Download transcript

Summary

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0:00.0

All right, welcome. This is episode 596 of the Divine Intervention podcast. In today's podcast,

0:07.1

we're going to be continuing the Step 13-120 series. This is going to be series 11B. Again,

0:14.7

God willing, series 12 will be the last. So here we're going to deal with, again, I want to do them in fives or tens.

0:22.3

So I'm going to do 106 to 110 here. And then, God willing, in probably in the next episode, we're just going to finish

0:28.5

up the remaining questions. All right. So question 106. I think the last podcast was kind of long

0:34.3

because 101 to 105 just had a lot of pretty high-year-old things to

0:37.6

discuss.

0:38.6

So question 10-year-old boy is brought to the physician because of a three-week history

0:44.0

of nosebleeds and easy bruiseability.

0:47.1

His older brother has had similar episodes.

0:50.0

He is at the 30th percentile for height and weight.

0:53.5

Fiscal examination shows nasal and ginger- bleeding and several echinoses over the trunk

0:58.2

and upper and lower extremities in various stages of healing.

1:03.3

Lap studies show a platelet count of 300,000, which is normal.

1:07.3

Platelet adhesion testing shows a normal response to ristocetin, but aggregation does not

1:12.9

occur in response to thrombin.

1:15.6

Platelet morphology is normal.

1:17.5

Prothrombing time and activated partial thromboplastin timer within the reference ranges.

1:23.3

A defect in which of the following is the most likely cause of the findings in this patient.

1:29.1

This is a very simple question if you understand primary hemostasis.

1:33.5

Remember, primary hemostasis has a bunch of steps, right?

1:36.3

So the very first step is the adhesion step where GP1B binds to von Willybran factor.

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