Welcome to episode 566 of the Divine Intervention Podcasts.

In today's podcast, we're going to be continuing our series on the Step 3, 3, 3137.

This is going to be part 12.

So we're going to pick up from question 11.

I begin.

A 24-year-old woman comes to the office because she had a positive home pregnancy test two days ago.

Urine pregnancy test in the office today is positive.

Physical examination findings are consistent with a 14-week gestation.

Ultrasonography shows a twin pregnancy with two female fetus.

This is her first pregnancy and she says she is concerned because she has a family history

of an eye disease in which

family members lose their vision beginning in their 20s. Testing of her vision today discloses no

abnormalities. The patient's pedigree is shown above. The patient is identified as IV, you know,

2, you know, 4th generation number 2. Which of the following is the most appropriate conclusion

about the inheritance of this disorder? So here's the trick. Whenever you get questions like this, you should go through every single answer. Pedigree questions, they're like, you should go through every answer. All right. First one says it's an orosomo dominant disorder. Well, remember, an orosomal dominant disorder, you know, if any one of your parents has the disorder, if you have even just one of the alleles, you're going to get in trouble.

Well, that doesn't really make any sense for this question, because if you notice, her dad had the problem.

And none of the kids have it.

That's just not really possible with an Orozumo Dominant disorder.

Because at least some of the kids got the

allele so you don't see any of them having the disorder so that's that's wrong all right if you have

an affected parent at least some of the oxpring will have the disorder right at least some of them

if not all of them if not all of them because at least one of them will have the affected all right? So some or all of them may have the problem. So that's wrong. Now, option B says it's a chromosomal aneuploidy. Well, think about it. What are the aneuploids that we know? You know, we have a trisomy 21. That's Down syndrome. That doesn't present with vision problems. We have trisomy 18. that's Edward syndrome that doesn't present with vision problems we have trisomy

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