4.9 • 759 Ratings
🗓️ 14 October 2025
⏱️ 24 minutes
🧾️ Download transcript
If you’ve ever seen beta glucuronidase pop up on your stool test and wondered what it actually means, this episode breaks it all down. This powerful enzyme made by bacteria in your gut can UNDO your body’s detox work by “unboxing” toxins and hormones that were meant to be eliminated, leading to bloating, breast tenderness, and stubborn weight gain, even when your estrogen levels look normal.
Erin walks through the 3-phase detox process and how gut imbalances, constipation, or low-fiber diets can allow estrogen and other toxins to recirculate in your system.
You’ll learn both short-term strategies like calcium D-glucarate and long-term fixes to bring your beta glucuronidase back into balance.
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| 0:00.0 | Gluceronidation combines these potentially toxic compounds with glucuronic acids to form a safer |
| 0:09.1 | substance. So these conjugates, these new compounds, are then suitable for safe elimination via |
| 0:16.7 | the biliary tract. So that's bile. It gets pulled into the stool through bile and then |
| 0:23.0 | ideally pooped out. So we are taking the toxins, pulling it through the body, and getting it |
| 0:28.8 | completely out of the body. That's the dream. That's the ideal. That's how this is all supposed to |
| 0:33.5 | work. Welcome to the functional nutrition podcast. spell it with a K, because we do things |
| 0:38.1 | a little differently around here. I'm your host, Erin Holt, and I've got 15 years of clinical |
| 0:42.4 | experience as a functional nutritionist and mindset coach, creating a new model that I call |
| 0:47.2 | intuitive functional medicine, where we combine root cause medicine with the innate intelligence |
| 0:51.8 | of your body. This is where science meets self-trust. Your body |
| 0:56.6 | already knows how to heal and this show is going to show you how. If you're looking for new ways of |
| 1:02.0 | thinking about your health, be sure to follow and share with a friend because you never know |
| 1:05.9 | whose life you might change. Hello, my friends. Today we are talking about beta glucuronidase. We're going to get right |
| 1:13.0 | into it. This whole show is dedicated to this one enzyme. This is one of the markers on the GI |
| 1:18.0 | MAP stool test. So if you've done a gut panel with us, you've seen it. And I loosely describe it |
| 1:23.8 | as a marker of detoxification, which is not inaccurate, but it's also not the whole |
| 1:30.0 | picture of exactly what is going on. So today, I want to paint that whole picture. We'll talk about |
| 1:36.0 | what it is and where it comes from, what it has to do with detox. If we see high beta glucoronidase |
| 1:42.2 | on a stool test, what does that mean? |
| 1:44.7 | And then what do we do about it? |
| 1:46.3 | What can we do to lower it? |
| 1:48.6 | So I was actually creating this as a resource for our clients because this is a marker |
... |
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