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BETTER! with Dr. Stephanie Estima | Strength, Body Composition & Perimenopause

Depleted, Foggy & Done? How Creatine Buffers Energy, Sleep Loss & Midlife Stress with Dan Pardi, PhD

BETTER! with Dr. Stephanie Estima | Strength, Body Composition & Perimenopause

Dr. Stephanie Estima

Intimacy, Menopause, Betterpodcast, Nutrition, Women's Health, Menstruation, Hormones, Optimization, Sex, Fitness, Sleep, Dr. Stephanie, Health & Fitness, Science, Parenting, Motherhood, Health, Self Care, Drstephanie, Mindset, Alternative Health, Self Love

4.8 β€’ 613 Ratings

πŸ—“οΈ 4 May 2026

⏱️ 93 minutes

🧾️ Download transcript

Summary

Dr. Dan Pardi β€” sleep researcher, neuroscientist, and Chief Health Officer at Qualia Life β€” breaks down the science of creatine that most women have never been told: why estrogen directly controls how well your cells absorb it, what three studies show it can do for a sleep-deprived brain, and how to actually start taking it without the bloating, the kidney fears, or the confusion.

Transcript

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0:00.0

You've spent your career studying the brain.

0:03.0

What is one thing that happens in your own brain that still surprises you?

0:07.0

I think that so much of our reality is us having a hallucination about the data that is being pulled in,

0:16.0

and then we create this interpretation of the world that is personal and may not be exactly what other people

0:22.4

are thinking or feeling or seeing. And that still shocks me. Creatines spent decades being a

0:29.9

gym bro supplement. So I consider myself a Jimbrough currently. Were you ever a Jimbrough?

0:35.5

Yeah. The first study that I ever took part in was in the mid-1990s, and we were looking at

0:41.7

creatine on exercise performance, and I took it for 20 years with that exclusive focus

0:49.6

in mind.

0:50.4

But my perspective has changed.

0:52.8

Finish this sentence in two sentences or less.

0:56.4

Most people think creatine is for blank, but it's actually for blank.

1:00.7

Most people think that creatine is for exercise performance, but it's really for energy support.

1:07.2

Nice.

1:08.5

You study sleep deprivation and decision making, so what is the worst decision you've personally made on bad sleep?

1:15.6

So here's the thing.

1:16.9

You tend to not realize you're making a bad decision when you're in the throes of sleep deprivation.

1:24.3

Only in hindsight can you look back and perhaps notice that you made a decision

1:29.9

that you would have not made if you had full sleep. Yeah, in hindsight, once you've had a great

1:36.0

sleep, you're like, yeah, maybe I shouldn't have, you know, held my horn on the road as long as I did.

1:46.4

Hello, my friends.

1:47.5

Welcome to another episode of Better with Dr. Stephanie.

...

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