Hello, residents. My name is Mike Estefan, and I thank you for joining me on this month's

deep dive episode on the EM Clerkship podcast. This month's deep dive is going to be covering

neuroleptic malignant syndrome, also known as NMS, for short. Before we begin, just a quick word from our sponsors over

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to mention EM clerkship if you do. And now, back to the episode. So today we're going to be

talking about neuroleptic malignant syndrome, again, NMS for short.

NMS is a clinical syndrome that can be seen in patients taking dopamine antagonists,

usually due to antipsychotics.

It is pretty rare, about one in five thousand patients who are prescribed antipsychotic medications will go on to develop

NMS. Despite the low incidence, the mortality rate is high. Different studies give different numbers,

but anywhere between 30 and 50% mortality rate for neuroleptic malignant syndrome. Because it is due to direct action of the medications

...