Decoding Skin Longevity with Timeline: The Mitochondrial Revolution ft. Jaimee Holmes
Skin Anarchy
Ekta et al.
4.2 • 2K Ratings
🗓️ 22 September 2025
⏱️ 29 minutes
🔗️ Recording | iTunes | RSS
🧾️ Download transcript
Summary
In this special masterclass of Skin Anarchy, Dr. Ekta sits down with Jamie Holmes, Chief Brand Officer of Timeline, to rethink skincare through the lens of longevity. Instead of chasing “anti-aging,” Timeline centers skin health span—keeping skin energetic, resilient, and vibrant for as long as possible. Holmes frames aging as a privilege and makes the case for supporting biology, not hiding it.
At the heart of the conversation is Urolithin A, the postbiotic behind Timeline’s proprietary MitoPure®. You’ll hear how this molecule triggers mitophagy—the cellular cleanup that renews tired mitochondria—so skin can generate more energy and recover from stressors faster. After a decade of research in nutrition, Timeline translated the clinically precise dose into topicals, creating a tight edit of formulas that show measurable gains in hydration and elasticity in as little as 15 days.
Jamie opens the lab door on formulation philosophy: no label dusting, just actives at proven concentrations, iterated for texture, absorption, and real-world performance. Even the details matter—the sustainable glass and aluminum, hygienic pumps, and that buttery-yellow hue that reflects MitoPure’s natural color—turning daily care into a gender-inclusive ritual. The lineup is intentionally minimalist, designed to slip into any routine and serve both biohackers and skincare newcomers who want evidence over hype.
If you’re curious about mitochondria as the next frontier in beauty—or you’re simply ready to trade quick fixes for cellular results—this episode is your guided tour. Tune in to learn how Timeline is redefining beauty with science you can feel and results you can see.
To learn more about Timeline, visit their website and social media.
CHAPTERS:
(0:02) – Introduction and Welcome
(1:05) – Redefining Anti-Aging and Skin Health Span
(3:30) – Mitochondria and Cellular Function
(5:20) – Early Signs of Aging and Skincare Gaps
(6:26) – Timeline’s Ingredient Integrity and Active Formulations
(8:00) – Urolithin A and MitoPure Science
(10:23) – Transition from Nutrition to Skincare
(14:44) – Product Development, User Experience, and Packaging
(20:08) – Longevity Consumer Mindset and Unisex Approach
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Transcript
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| 0:00.0 | Hey guys, welcome back to Skin Anarchy. This is a very special episode and it is kicking off our masterclass with the iconic brand timeline. I know you guys have heard about them before. We've hosted them once previously on the show and I am a huge fan of what they're doing, how they're approaching skin health, rather than focusing on |
| 0:22.1 | these anti-aging claims that we've been seeing for so many decades now in the beauty space. |
| 0:26.9 | So I think this is a whole new lens to look through when it comes to skin health and skin science. |
| 0:32.1 | So without me ranting too much, please welcome back, Jamie Holmes, who is the chief brand officer for Timeline. Welcome, |
| 0:38.8 | Jamie. I'm so excited for us to chat today. Thanks so much for having me. I'm so excited to chat, too, and tell you all the new things we've been cooking up over here. Yeah, you guys have been killing it. You know, I've been watching and I've been following along. And I think, you know, Just like I said, you know, the approach timeline is taking is just so exciting, you know, for me as a consumer because long needed. We've been waiting for this for a long time. |
| 1:01.4 | Oh, thank you. Yeah, but I want to talk to you about, you know, this whole narrative around anti-aging and how you guys are kind of redefining that, you know? Can you tell us, like, you know, |
| 1:11.6 | why has timeline made such a conscious shift towards supporting things like skin health span instead? |
| 1:17.7 | And what does that actually mean at the cellular level? So I think what's really special about |
| 1:24.3 | the brand and certainly what drew me to the brand is the incredible honest scientific rigor |
| 1:30.3 | behind it i think the fact that timeline really spent more than 10 years developing the ingredient |
| 1:37.7 | studying the ingredient understanding its impact internally and externally is such a testament to what they've built really as a |
| 1:46.3 | longevity leader. And I think that's so, so important because truly we didn't commercialize |
| 1:51.8 | products until five years ago. We started with nutrition. Skin care is still so extremely |
| 1:57.7 | new and exciting and emerging within our business. We started that about two years ago. |
| 2:03.8 | And I think just to talk about in general, just the conversation of longevity and how we're defining |
| 2:10.1 | that, we don't use the words anti-aging for a reason, as you said. For us, it's really about |
| 2:16.4 | feeling your best, feeling your healthiest for as long |
| 2:20.3 | as possible. And that's really how we define it. We say, you know, living is in our longevity is the |
| 2:26.4 | science behind it. And our goal is really just to empower people to master both on their journey |
| 2:32.7 | of a life from the course of their own timeline. |
| 2:35.9 | Right. No, I think that is just, it's so, so new to so many consumers, but it's like, |
| 2:42.4 | we've never thought about it like that, you know, with skincare, because for so long, I mean, |
... |
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