Usually it's anadrol. People go into the competitions, usually you'll see the, especially the heavy, super heavy weights.

On the day of the competition, you'll see them blue, if they're white people, they'll look like blue because of the amount of anadrol they took.

I don't know what it does to blood circulation, but it ends up being where you look a little bit blue and like you've just died.

Wow. That's one of the most confusing compounds when you actually look at the pharmacodynamics of it

and how it's working.

It's like inherently like prevents estrogen clearance.

And then it's also like progestogenic somehow.

Even though it's chemical structure is a DHD derivative.

It's like one of the most confusing anabolic I've ever seen to learn. And it also,

it's affinity for the androgen receptor is undetectable. It's like what the fuck is going on

with that compound? Why do you say the affinity for the androgen receptors undetectable? I never

of that before. Oh, you've never seen like the binding assay studies where they check, you know,

relative to primo, relative to nandrolone. And it was like the lowest ones were like d-ball um i don't remember

what they were but at the very bottom of the totem pole anandrol was undetectable and it's binding

affinity for ar so but the thing about binding affinities right is that they see nothing about

the efficiency or efficacy of of causing response elements from the binding.

So for example, you can have something that doesn't have a strong affinity for the androgen receptor, but when it does bind to it, causes an immediate response, right?

Right.

Or you could have something like, are you, that stuff you guys use on your hair, where that just holds onto the receptor but doesn't activate it that fully.

Right. So the, like I would assume anadryl has a lot of like satellite interactions with other receptors that you would not traditionally think of because everyone just thinks how potent of an agonist of the AR is it.

But I've never seen anyone give like an elaborate

good explanation of how it's doing what it's doing. I don't know, that'd be interesting

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