Dec 3, 2021 This Week in Cardiology Podcast
This Week in Cardiology
Medscape Podcasts
4.9 • 963 Ratings
🗓️ 3 December 2021
⏱️ 20 minutes
🧾️ Download transcript
Summary
The AMAZE trial of left atrial appendage isolation, non-statin oral lipid lowering drugs, EHR alerts, non-MD care, and obesity are the topics John Mandrola, MD, discusses in this week's podcast. To read a partial transcript or to comment, visit: https://www.medscape.com/twic
I – aMAZE Trial
- No Advantage Shown for LAA Ligation as Adjunct to Pulmonary Vein Isolation https://www.medscape.com/viewarticle/962954
- Safety and Procedural Success of Left Atrial Appendage Exclusion With the Lariat Device https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2289126
- Left Atrial Appendage Isolation in Patients With Longstanding Persistent AF Undergoing Catheter Ablation: BELIEF Trial https://pubmed.ncbi.nl m.nih.gov/27788847/
II – Non-Statin Lipid Lowering
- Obicetrapib: CETP Inhibitor Impresses in LDL Lowering https://www.medscape.com/viewarticle/963611
- Daily Oral PCSK9 Inhibitor Encouraging in Phase 1 Trials https://www.medscape.com/viewarticle/963550
III – EHR Alerts and Prognosis
- EHR Alerts Have No Impact on Inpatient HF Treatment or Outcomes https://www.medscape.com/viewarticle/963002
- REVeAL-HF: Design and Rationale of a Pragmatic Randomized Controlled Trial Embedded Within Routine Clinical Practice https://www.jacc.org/doi/full/10.1016/j.jchf.2021.03.006
IV – Non-MD Care Models
- Remote Non-Physician Care Helps BP, LDL Control https://www.medscape.com/viewarticle/963783
- A Remotely Delivered Hypertension and Lipid Program in 10,000 Patients Across a Diverse Health Care Network https://www.abstractsonline.com/pp8/?_ga=2.141042993.2042594723.1635046736-1021258137.1633710264#!/9349/presentation/18153
V – Obesity in the Young
- Obesity Rates Soar in Early Adulthood in the US https://www.medscape.com/viewarticle/963511
- Trends in Obesity Prevalence Among Adults Aged 18 Through 25 Years, 1976-2018 https://jamanetwork.com/journals/jama/article-abstract/2786516
Features
- Doubting the BELIEF Trial on LAA Isolation https://www.medscape.com/viewarticle/850822
You may also like:
Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine https://www.medscape.com/features/public/machine
The Bob Harrington Show with Stanford University Chair of Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington
Questions or feedback, please contact news@medscape.net
Transcript
Click on a timestamp to play from that location
| 0:00.0 | You're listening to this week in cardiology from the heart.org on medscape. |
| 0:09.7 | You can now access the latest in medical news on your Amazon Alexa enabled device. |
| 0:14.3 | Join me, Perry Wilson, every weekday morning for Medscape Medical Minute, where I highlight |
| 0:18.8 | the top medical stories of the day. |
| 0:21.1 | To add Medscape Medical Minute to your flash briefing, search for Medscape |
| 0:24.4 | Medical Minute on Amazon and click enable. Or open the Amazon Alexa app, go to |
| 0:29.0 | skills, search for Medscape Medical Minute and click enable. Then say, |
| 0:33.4 | Alexa, what's the news or Alexa, what's my flash briefing? I hope you'll join us. |
| 0:38.6 | Hi everyone, this is John Mandrola from the Heart.org Medscape |
| 0:42.8 | cardiology and this is this week in |
| 0:45.0 | cardiology for December 3rd 2021. |
| 0:49.2 | This week, the Amaze trial, non-Statined Oral Lippid Lowering Drugs, |
| 0:55.0 | EHR Alerts, Non-physician Care, and Obesity. |
| 1:01.0 | First up is the Amaze Trial and Left Atrial Appended. and more destruction in the left atrium improves ablation outcomes. |
| 1:15.0 | Now in patients with persistent or long-standing persistent AFIB |
| 1:18.0 | AMaze trial tested weather add-on left atrial-appended |
| 1:22.6 | ligation with the Lariat device would reduce AF |
| 1:26.4 | compared with standard AF ablation alone, which was PBI. |
| 1:30.2 | The answer was no. |
| 1:31.2 | There was no statistical reduction of AF with more extensive work in the left atrium. |
| 1:35.8 | But Amaze teaches us many other lessons relevant to, say, regulatory approval, critical appraisal, and the value of a medically conservative approach to procedures. |
| 1:48.0 | Now first some specifics on the Amage trial, this was 610 patients randomized with advanced forms of a fib. The |
... |
Please login to see the full transcript.
Disclaimer: The podcast and artwork embedded on this page are from Medscape Podcasts, and are the property of its owner and not affiliated with or endorsed by Tapesearch.
Generated transcripts are the property of Medscape Podcasts and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.
Copyright © Tapesearch 2026.