Dec 01 2023 This Week in Cardiology
This Week in Cardiology
Medscape Podcasts
4.9 • 963 Ratings
🗓️ 1 December 2023
⏱️ 28 minutes
🧾️ Download transcript
Summary
More from AHA including SGLT2 inhibitors, blood transfusion after MI; cracks in the armor of Factor XI inhibitors; and renal denervation are the topics John Mandrola, MD, covers in this week's podcast.
This podcast is intended for healthcare professionals only.
To read a partial transcript or to comment, visit:
https://www.medscape.com/twic
I. DAPA MI
Potential Dapagliflozin Benefit Post-MI Is Not a 'Mandate'
https://www.medscape.com/s/viewarticle/998378
- NEJM Evidence: Dapagliflozin After MI https://evidence.nejm.org/doi/full/10.1056/EVIDoa2300286
II. Blood Transfusion Strategy Post MI
In MI With Anemia, Results May Favor Liberal Transfusion: MINT
https://www.medscape.com/viewarticle/998376
- MINT NEJM -- https://www.nejm.org/doi/full/10.1056/NEJMoa2307983
- REALITY https://jamanetwork.com/journals/jama/fullarticle/2776201
- PROTECTED TAVR - https://www.nejm.org/doi/full/10.1056/NEJMoa2204961
III. FACTOR XI
Impressive Bleeding Profile With Factor XI Inhibitor in AF: AZALEA
https://www.medscape.com/viewarticle/998418
Asundexian Phase 3 AF Study Halted for Lack of Efficacy
https://www.medscape.com/viewarticle/998665
- Abelacimab for VTE https://www.nejm.org/doi/full/10.1056/NEJMoa2105872
IV. Renal Denervation
FDA Panel Split on Efficacy of Spyral Renal Denervation
https://www.medscape.com/viewarticle/995800
FDA OKs Symplicity Renal Denervation System for Hypertension
https://www.medscape.com/viewarticle/998664
- SPYRAL HTN OFF MED -- https://doi.org/10.1016/S0140-6736(20)30554-7
- SPRYAL HTN On Meds (Pilot Lancet 2018 ) https://doi.org/10.1016/S0140-6736(18)30951-6
- SPRYAL HTN ON Meds (Expansion Pilot) https://doi.org/10.1016/j.jacc.2023.08.045
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Questions or feedback, please contact news@medscape.net
Transcript
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| 0:00.0 | You're listening to this week in cardiology from the heart |
| 0:03.4 | org medscape cardiology this podcast is intended for health care |
| 0:07.6 | professionals only any views expressed are the presenters own and do not |
| 0:11.2 | necessarily reflect the views of WebMD or Medscape. |
| 0:15.1 | You can now access the latest in medical news on your Amazon Alexa-enabled device. |
| 0:19.9 | Join me, Perry Wilson, every weekday morning for Medscape Medical Minute where I highlight the top |
| 0:24.7 | medical stories of the day. |
| 0:26.5 | To add Medscape Medical Minute to your flash briefing, search for Medscape Medical Minute on Amazon |
| 0:31.3 | and click enable or open the Amazon Alexa app go to skills |
| 0:34.7 | search for Medscape Medical Minute and click enable then say Alexa what's the |
| 0:40.1 | news or Alexa what's my flash briefing I hope you'll join us. |
| 0:44.0 | Hi everyone this is John Mandrola from the Heart.org medscape and this is this |
| 0:50.0 | week in cardiology for December 1st, 2023. This week we'll have more from the |
| 0:56.1 | AHA. This includes SGLT 2 inhibitors after MI, blood transfusion |
| 1:02.0 | strategies after MI. I. A crack in the armor of factor 11 |
| 1:06.9 | inhibitors and more on renal denervation. First up is the DAPA M.I trial. This was presented at AHA. The SGLT 2 inhibitor class of drugs have as positive, |
| 1:20.0 | both tons of empirical data and they're also easy to use. |
| 1:24.0 | In chronic kidney disease, and diabetes, and heart failure, there are clear benefits. |
| 1:29.0 | Now we can debate cost efficacy, but there are surely benefits. What about in post-MI patients? |
| 1:36.7 | Swedish investigators' first author, Stefan James, tested the idea of adding Dabaglip |
| 1:41.7 | Wilson to patients after an MI that either left the patient |
| 1:45.9 | with a Q wave on the EKG or mild left intrigular dysfunction. |
... |
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