David Sinclair (Harvard Professor) Reveals Age-Reversing Science to Look & Feel Younger
Moonshots with Peter Diamandis
PHD Ventures
4.8 • 605 Ratings
🗓️ 24 February 2026
⏱️ 144 minutes
🔗️ Recording | iTunes | RSS
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| 0:00.0 | Have we reached some state of age reversal technology that truly works? |
| 0:05.0 | We can cure diseases and injuries that have never been cured before. |
| 0:09.0 | And so imagine in 10 years you just take a pill for four weeks and you get younger. |
| 0:14.0 | Why do we age? |
| 0:17.0 | The epigenome is the issue because going through sperm and egg and fertilization resets the epigenome. But the good news is we've figured out |
| 0:25.6 | a way to safely reset that without having to clone yourself. |
| 0:28.6 | We've gone from the idea that, oh, we just take a supplement or we do some exercise |
| 0:32.6 | to slow down aging. Now we're talking about the ability to truly reset the body, reset all of the |
| 0:38.9 | cells in the body to be young again. Teenager today will live into the 22nd century. |
| 0:47.4 | Now that's the moonshot, ladies and gentlemen. Welcome to moonshots, everybody. Today's episode is delivering on a state of the union on age reversal, |
| 0:59.5 | focusing on one of my favorite moonshots, longevity. We'll be discussing epigenetic reprogramming, |
| 1:05.7 | when we might reach longevity escape velocity, and the role of AI in our longevity quest. My guest here is a dear friend, |
| 1:13.5 | a brilliant scientist, Dr. David Sinclair, professor at Harvard Medical School, author of Lifespan, |
| 1:18.9 | one of my favorite books. We'll talk about what comes next from David's authorship, |
| 1:23.5 | and one of the leading thinkers in the realm of age reversal, epigenetics, and longevity |
| 1:29.1 | science. We'll discuss what's here on the near term, how you can support it, how you can be |
| 1:35.1 | involved in it, how you can benefit from it. We'll also discuss why at age 55, David looks like |
| 1:41.3 | he's 35. I believe we're living during the most extraordinary times in human history. And if you want to see more of this future, if you want additional decades in your life, this is the episode for you. All right. Let's jump in with Dr. David Sinclair and a whole download on the state of age reversal. David, welcome, buddy. Hey, Peter. It's good to be back. It's good to have you back. How are you doing? I'm doing well, you know. I'm having a blast. I am more focused on my health than I ever have been. You're looking really good. I was commenting on your biceps right now. That's why I'm wearing a jacket here because I don't have them. |
| 2:18.3 | I think, and we can talk about this, that in fact, muscle mass and exercise still remains one of the primary pro-Longevity drugs out there. |
| 2:27.3 | Absolutely. |
| 2:28.3 | Yeah. |
| 2:29.3 | And, you know, we'll get into the details of what the best day of the art is and what's coming because, |
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