CRISPR, Colors, Narwhals. June 15, 2018, Part 2
Science Friday
Science Friday and WNYC Studios
4.4 • 6.3K Ratings
🗓️ 15 June 2018
⏱️ 47 minutes
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| 0:00.0 | This is Science Friday. I'm Ira Flato, coming to you today from the studios of WBEZ in Chicago. |
| 0:07.1 | Later this hour, the chemistry and light tricks that bring us the rainbow, the science of colors. |
| 0:12.9 | First, one of the scientific advances that's taken the biology world by storm is the gene editing |
| 0:19.5 | technique known as CRISPR. It allows researchers to |
| 0:23.0 | fairly easily make edits to genes, sniffing out one sequence, inserting another in its place, |
| 0:29.6 | but it appears there could be a downside to the technique. Joining me now to talk about it is |
| 0:35.0 | Sharon Begley. She's senior science writer at Stat News, based in Boston, and author of an article this week |
| 0:41.4 | about new research findings in the CRISPR world. |
| 0:44.1 | Welcome back to the program, Sharon. |
| 0:46.1 | Thank you for having me, Ira. |
| 0:48.0 | So tell us about this. |
| 0:49.4 | What exactly did these research papers find? |
| 0:53.3 | These were two papers published earlier this week in the journal Nature Medicine, |
| 0:58.0 | and they both converged on a similar conclusion. |
| 1:01.6 | Both used CRISPR, which, as you described, is the latest genome editing technique, to alter cells. |
| 1:08.3 | One group used stem cells, the other group used eye cells, both human. |
| 1:14.6 | And they found that it was much easier to CRISPR the cells, but we're now using CRISPR as a verb, |
| 1:22.6 | if those cells lacked a key anti-cancer gene and anti-cancer pathway. |
| 1:29.9 | So to flip that around, if cells are successfully edited, if their genomes are successfully edited |
| 1:36.8 | with CRISPR, that raises a concern that maybe there's something wrong with those cells, |
| 1:41.5 | i.e. that they lack a crucial anti-cancer pathway. |
| 1:45.0 | So that's all that the studies did. They didn't find that anybody was going to get cancer from |
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