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Nature Podcast

Coronapod: The divisive hydroxychloroquine study that's triggering mass confusion

Nature Podcast

podcast@nature.com

News, Science, Technology

4.5893 Ratings

🗓️ 29 May 2020

⏱️ 27 minutes

🧾️ Download transcript

Summary

00:59 Chloroquine on rocky ground

President Trump's preferred coronavirus treatment is the focus of a new study suggesting it could cause more harm than good, but not everybody agrees. We discuss the fallout as trials around the world are paused and countries diverge over policy advice.

News: India expands use of controversial coronavirus drug amid safety concerns

News: Safety fears over hyped drug hydroxychloroquine spark global confusion



12:12 Are we rushing science?

Coronavirus papers are being published extremely quickly, while normally healthy scientific debate is being blown up in the world’s press. Is there a balancing act between timely research and accurate messaging?


18:49 One good thing

Our hosts pick out things that have made them smile in the last week, including hedgerow brews and a trip into the past using AI.

Recipe: Elderflower 'Champagne'

Video: Denis Shiryaev restores historic footage with AI


22:30 The latest coronavirus research papers

Noah Baker takes a look through some of the key coronavirus papers of the last few weeks.

News: Coronavirus research updates

medRxiv: Full genome viral sequences inform patterns of SARS-CoV-2 spread into and within Israel

Harvard Library: Reductions in commuting mobility predict geographic differences in SARS-CoV-2 prevalence in New York City

Science: DNA vaccine protection against SARS-CoV-2 in rhesus macaques


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Transcript

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0:00.0

Welcome to CoronaPod. In this show, we're going to bring you nature's take on the latest COVID-19 developments.

0:09.1

And we'll be speaking to experts around the world about research during the pandemic.

0:15.4

I really don't know how this plays out. We also don't know a ton about this, you know, virus. So there's so many open

0:21.0

questions. I just have a really hard time making predictions because I don't know how the outbreak's

0:25.6

going to change. Hello and welcome to episode 11 of CoronaPod. My name's Noah Baker,

0:34.3

and I'm joined by Features editor Richard Van Norton. Unfortunately, CoronaPod regular Amy Maximum is not able to be with us this week,

0:41.7

but Richard and I are going to power on anyway and see if we can bring you some latest news.

0:46.9

Richard, how's your week been?

0:48.0

Yeah, it's been pretty good, thanks, Noah.

0:49.7

I had the day off on Monday.

0:51.5

Went for a long walk, so I'm rejuvenated. Rejuvenated. I think as far as one

0:56.2

can be rejuvenated at the moment. That's right. So this week, we're going to talk about something

1:01.1

that we have actually talked about before on CoronaPod, but we're going to dig into a little bit,

1:05.9

which is hydroxychloroquine. Now, this is a potential treatment for COVID-19, which has been

1:12.4

bandied about by many people. There are lots and lots of trials and studies that have been going,

1:18.4

and this week there's been a whole new development or a whole new series of developments with

1:23.1

hydroxychloroquine. So first off, I think the biggest news has been there was a paper release from

1:28.9

the Lancet of a large observational study. Richard, tell me what's going on with that. Yeah, so this paper

1:34.7

was a huge study, but it was observational, as you say, meaning that it's not a randomised

1:41.9

controlled trial. They're not dividing their patients randomly

1:45.8

into matched groups and giving some hydroxychloroquine and some not without knowing who.

1:51.4

That's the gold standard. That's some of the trials underway. This, they just looked at many

...

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