Coronapod: the biomarker that could change COVID vaccines
Nature Podcast
podcast@nature.com
4.5 • 893 Ratings
🗓️ 2 July 2021
⏱️ 17 minutes
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Summary
Since the beginning oft he pandemic, researchers have searched for a biomarker which indicates immune protection from COVID-19 known as a correlate of protection. Now, the team developing the Oxford–AstraZeneca COVID-19 vaccine have published the first results of their so-called 'breakthrough study' which indicated puts forwards thresholds of neutralising antibodies that they suggest correlate with protection. The hope is that, should these results be confirmed, such biomarkers could speed up the development of new vaccines, and provide better ways to monitor the efficacy of tweaked vaccine aimed at fighting variants.
News: Scientists identify long-sought marker for COVID vaccine success
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| 0:00.0 | The Nature podcast is supported by Nature Plus, a flexible monthly subscription that grants immediate online access to the Science Journal Nature and over 50 other journals from the nature portfolio. |
| 0:11.7 | More information at go.nature.com slash plus. |
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| 0:48.4 | Welcome to Corona Pod. In this show, we're going to bring you nature's take on the latest COVID-19 developments. |
| 0:57.7 | And we'll be speaking to experts around the world about research during the pandemic. |
| 1:04.0 | We're entering a new era now. We have new COVID strategies. |
| 1:07.9 | There's some new unknowns and we've got a vaccine. |
| 1:14.4 | Hello. COVID strategies. There's some new unknowns and we've got a vaccine. Hello and welcome to Corona Pod. I'm Noah Baker and joining me this week is CoronaPod regular |
| 1:19.6 | Ewan Calloway. You and how are you? And well, how are you doing? Not bad, thanks. So you as ever |
| 1:25.2 | are beavering away writing story after story after story about coronavirus. |
| 1:29.3 | And the story you're publishing this week is one that's been quite a long time coming about |
| 1:34.2 | correlates of protection. Now, there's a lot to dig into here. But to start with, can you tell me |
| 1:38.1 | what we mean when we say correlates of protection? Yeah. So it's looking at COVID-19 vaccines or vaccines in general. And, you know, anytime you |
| 1:47.9 | have a vaccine, unless it's 100% effective, there are going to be people who get vaccinated |
| 1:53.9 | and unfortunately still get infected. And then, you know, the vast majority of people who are |
| 1:59.7 | protected by the vaccine. |
| 2:06.0 | So a correlative protection is an immune measurement or some kind of measurement or biomarker that tells you which is which, you know, which people are going to be protected and which people |
| 2:09.9 | might not be. And this is a really important and useful marker for immunologists, people that are designing vaccines to know. |
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