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Nature Podcast

Coronapod: Infected immune cells hint at cause of severe COVID

Nature Podcast

podcast@nature.com

News, Science, Technology

4.5893 Ratings

🗓️ 15 April 2022

⏱️ 13 minutes

🧾️ Download transcript

Summary

Since the beginning of the pandemic there has been a debate amongst researchers about whether the body's immune cells can themselves be infected by SARS-CoV-2. Now two new studies show that they can - and what's more, the work has revealed a new mechanism for the massive inflammatory response seen in severe COVID. In this episode of Coronapod, we dig into the papers, asking why it has taken so long to get an answer to this question? How immune cell infection could lead to severe disease? And whether this new mechanism could provide a new avenue for the development of therapeutics?


News: What triggers severe COVID? Infected immune cells hold clues


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Transcript

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0:00.0

At three business, we know the importance of keeping your business connected.

0:04.8

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0:10.6

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0:46.7

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0:50.6

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0:53.8

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0:59.0

Welcome to CoronaPod.

1:05.6

In this show, we're going to bring you nature's take on the latest COVID-19 developments.

1:11.4

And we'll be speaking to experts around the world about research during the pandemic.

1:17.8

We're entering a new era now. We've new COVID strategies. There's some new unknowns and we've got a

1:23.8

vaccine.

1:29.7

Hello and welcome to Corona Pod.

1:35.4

I'm Noah Baker, and joining me this week is senior reporter in our Asia-Pacific Bureau, Smriti Malapati.

1:36.1

Smriti, how are you?

1:37.5

Hi, I'm well, thanks.

1:40.4

What we're going to talk about today is severe COVID.

1:44.9

Now, we'll get on to the severe COVID part in a minute, but I want to kind of build this story up because there's quite a lot of layers. And the first driver of this story is a seemingly

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