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Paul Saladino MD podcast

Controversial Thoughts: Should you worry about vitamin A toxicity from liver?

Paul Saladino MD podcast

Paul Saladino, MD

Medicine, Health & Fitness

4.82.7K Ratings

🗓️ 7 May 2021

⏱️ 32 minutes

🧾️ Download transcript

Summary

Short answer: No.
Listen to this week's episode of Controversial Thoughts for the full breakdown. Come down the rabbit hole with me!
Here's are the cliff notes: In amounts consistent with what we would find in nature, there's no evidence that vitamin A is an issue and lots of evidence that the unique nutrients found in it are invaluable for optimal human health.
It's also totally safe for pregnancy in ancestrally consistent amounts (1-2 oz per day, ~ 8oz per week, or 6-12 capsules of Bone Marrow & Liver from @heartandsoilsupplements)
Don't trust, verify. Include liver in your life and see how you feel! I'm betting, you're going to level up in many ways!
#theremembering

Transcript

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0:00.0

What is up you guys? Welcome to another edition of Controversial Thoughts. I have been getting tons of questions about vitamin A toxicity, possibly related with liver consumption.

0:12.0

And so I wanted to do a controversial thoughts video all about this to really lay it out for you guys and give you all the details and give you my thoughts on this.

0:22.0

If you just want the crib notes, I don't have concerns about vitamin A toxicity related to liver consumption, especially grass fed, grass finished, regeneratively raised liver, the kind that we only use in hard and soil supplements, the kind that you can get from the right type of farms that you should be supporting in reasonable doses, like what you would be expected or reasonably encounter in a hunter gatherer environment.

0:51.0

Meaning when I was with the HODZA and we killed to go, one of the HODZA tribe members took the liver out and literally treated it like it was made of a Faber J egg.

1:05.0

It was so careful with it. He gently placed it on a rock. They took such care with the liver, much more care than any of the other organs. They clearly prized the liver and they cut maybe an ounce off and they gave it to each of us.

1:19.0

You can imagine that the day before we had baboon, we had a little bit of liver from the baboon, we had a little bit of liver from the goat.

1:28.0

It's probably not evolutionarily consistent to be eating a pound of liver per day, but reasonable amounts of liver, an ounce, two ounces, three ounces of liver a day, is probably reasonably...

1:45.0

Within the realm of what you might find in the natural world and you're eating it with other organs and with muscle meat as you hear in this video it all works synergistically.

1:54.0

So I have no concerns about vitamin A from liver, vitamin A toxicity from liver consumed in those amounts that are evolutionarily consistent, that are ancestrally consistent.

2:07.0

When we formulate our supplements, when I formulate it all of these, you'll see that the amount of liver in these supplements is moderate. It's enough to give you the benefits without getting you anywhere near any dose of vitamin A that could be in any way shape or form worrisome for toxicity.

2:23.0

So let's begin at the beginning here. Let's use our brains. Let's use our noggins and think intuitively about this. Let's be reasonable.

2:32.0

Does it make any sense for this prized organ from all sorts of hunter gatherer tribes all throughout human evolution that has so many nutrients in it that are difficult to obtain other places, biotin, vitamin A, folate, riboflavin, peptides, manganese, zinc, copper, which is valuable.

2:56.0

Let's talk a little bit about copper in this video too. So many compounds, vitamin K2, colonine, the list goes on and on that are uniquely found in liver.

3:06.0

Does it make any sense for this to be bad for us? No, absolutely not. And there's no historical precedent for this.

3:13.0

So we can have 10 massive amounts of fat soluble vitamins like vitamin E, vitamin D, vitamin A, or vitamin K2, be harmful for humans. Yeah, probably. But we would never obtain massive amounts of these items evolution evolutionarily.

3:30.0

And if we're eating animals and not eating supplements, we're going to have a really hard time. And I mean synthetic supplements of vitamin A. We're going to have a really hard time getting to toxic levels of any of these fat soluble vitamins.

3:45.0

We could also sitting the same thing about vitamin D. Our body has a way of moderating the amount of vitamin D that we're going to convert from 25 hydroxides to 125 hydroxid vitamin D at the level of the kidney.

3:56.0

But when you're in the sun, like I am a lot, if you're watching a YouTube video, you know that I'm pretty tan right now. My body is making a lot of 25 hydroxid vitamin D, but it's regulating how much 125 hydroxid vitamin D gets made.

4:07.0

There are stopgaps in place. And what you will find if you look at the fat soluble vitamins, that would be ED, A and K2, or all of the K isomers, both the menopronones and the phylocronones, they all work in tandem.

4:21.0

And also vitamin D can actually affect how your body metabolizes vitamin A. It just all works evolutionarily. And as we're here in this video, other nutrients found in animal meat and organs like zinc can play a crucial role, or they do play a crucial role in vitamin A metabolism and zinc deficiency could worsen vitamin A toxicity.

4:44.0

And getting large amounts of fat soluble vitamins in isolation, like we might if we're taking synthetic supplements that are not whole forms of organs or animal foods, that could throw things out of whack as well.

4:56.0

There's a really elegantly designed natural system here, guys, that if you are eating animals from nose to tail, as the majority of your diet, the type of diet I'm so excited about, we might call it a hashtag animal based diet.

...

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