Clinical trials, Yellow cards, Chemo brain, Conduct Disorder
Inside Health
BBC
4.4 • 575 Ratings
🗓️ 26 February 2013
⏱️ 29 minutes
🧾️ Download transcript
Summary
Dr Mark Porter puts the Pharmaceutical Industry in the spotlight as some clinical trials are criticised for testing new drugs against a weaker rival so that the results appear much better than they really are. Kamran Abbasi takes on Dr Bina Rawal from the Association of British Pharmaceutical Industry to discuss if the hurdles are being set too low, so that a new therapy comes out on top.
And what if sustained periods of adversity in childhood are associated with permanent structural changes in brain development? So suggests new research into adolescents with Conduct Disorder - a controversial diagnosis given to 1 in 20 teenagers in the UK with aggressive or anti-social behaviour. Many of these children will have been exposed to severe abuse, but do these findings have implications for common family discord that lasts months or years? Mark Porter investigates.
Transcript
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| 0:00.0 | Hello, I'm Greg Jenna and good news, Your Dead to Me is back for a new series. Here we go. Yes, we'll explore Emperor Nero's notorious reign with Professor Marybeard and Patton Oswald. I would not want my daughter having the remote control, not alone an empire. We'll dissect the decadent life of Philippe Duke-Dor-Leon with Tom Allen. I've often tried to pretend I'm an aristocrat and being very quickly knocked down. And there'll be so much more with comedians like Olga Koch, Mike Mosniak and Rihalina. I'm excited. You're dead to me, the comedy podcast that takes history seriously. Listen first on BBC Sounds. Hello, I'm Dr Mark Porter and thank you for downloading this edition of Inside Health. |
| 0:37.8 | I hope you enjoy it. |
| 0:39.2 | Coming up today, how your upbringing might determine your future. |
| 0:43.2 | We examine the implications of new research, |
| 0:46.0 | suggesting that sustained periods of adversity in childhood |
| 0:48.9 | are associated with permanent changes in brain structure and function, |
| 0:52.8 | something that's bound to worry any family |
| 0:54.6 | struggling to deal with challenges like abuse, deprivation or marital discord. |
| 0:59.2 | I couldn't understand why I'd become the person I had |
| 1:04.2 | or why I felt like I needed to deal with that the way I did. |
| 1:09.7 | But is it cause or effect? |
| 1:11.4 | We'll find out what the experts think later on. |
| 1:14.3 | First, drug trials. |
| 1:15.9 | The pharmaceutical industry has been criticised recently |
| 1:18.4 | for burying results that fail to show their products in a good light. |
| 1:22.7 | But now there's growing concern that some trials are being conducted in a way |
| 1:26.3 | that's likely to make a new drug |
| 1:28.1 | look to be more of an advance than it really is. Using a simple analogy, if I wanted to make myself |
| 1:34.0 | appear to be a good runner, I'm unlikely to take on Usain Bolt, because I'd look a lot quicker |
| 1:38.9 | up against Fatti R Buckle. And that's essentially what trial organisers are being accused of. Inside |
| 1:44.0 | Health, Dr Cameron Abassi has been investigating. Yes, it's an issue that's essentially what trial organisers are being accused of. Inside Health, Dr Cameron |
| 1:44.7 | Abbasi has been investigating. Yes, it's an issue that's been bubbling under for quite a number of |
... |
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